Evidence map›Paper›PMID 40528844›Full record

SynthesisFrontiers in psychology2025

The effect of alexithymia on depression: evidence from meta-analysis.

Zhijun Liu, Shiwei He, Chunna Hou

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhijun LiuDepartment of Sociology, Changchun University of Science and Technology, Changchun, China.
Shiwei HeDepartment of Sociology, Changchun University of Science and Technology, Changchun, China.
Chunna HouSchool of Psychology, Northeast Normal University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Depression is primarily characterized by persistent low mood and cognitive dysfunction, whereas whereas alexithymia refers to difficulties in cognitively processing emotions. Although alexithymia being recognized as a risk factor for depression, there is no clear scholarly consensus on its exact role. Methods: This investigation employs a meta-analytic random effects model to examine the relationship between alexithymia and depression. The analysis draws on data from 35 studies involving 23,085 individuals. Results: Several key findings are revealed: Firstly, the total alexithymia score shows a positive correlation with depression severity, possibly influenced by cultural differences between Eastern and Western populations. Secondly, Difficulty in Describing Feelings (DDF) and Difficulty in Identifying Feelings (DIF) are significantly associated with depression, while Externally Oriented Thinking (EOT) has a weaker link. Thirdly, the relationship varies across different demographic groups and depends on the depression assessment tool used. Discussion: These results emphasize the importance of examining not only the overall relationship between alexithymia and depression but also its specific dimensions. Additionally, the study explores the rational explanation of the interplay between alexithymia and depression within a Chinese cultural context and within the framework of the interpersonal theory of depression.

Indexed as

alexithymiadepressiondifficulty in describing feelingsdifficulty in identifying feelingsexternally oriented thinkingmeta-analysis

Identifiers

PMID40528844
PMCPMC12171140

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.