Role for Left Dorsomedial Prefrontal Cortex in Self-Generated, but not Externally Cued, Language Production.

Deborah Levy, Quinn Greicius, Catherine Wang, Edwin Ko, Duo Xu, John Andrews, Edward F Chang

Abstract read

In one paragraph

Article in Neurobiology of language (Cambridge, Mass.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Multimodal imaging and machine learning for diagnosis of Parkinson's disease with cognitive impairment: ASL and QSM as potential biomarkers.Frontiers in aging neuroscience · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deborah LevyDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-1389-2525

Quinn GreiciusDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-3899-9855

Catherine WangDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0009-0004-2185-7166

Edwin KoDepartment of Linguistics, Yale University, New Haven, CT, USA.ORCID https://orcid.org/0000-0002-8275-9859

Duo XuDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-8259-8688

John AndrewsDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-8025-1525

Edward F ChangDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.ORCID https://orcid.org/0000-0003-2480-4700

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The left dorsomedial prefrontal cortex (dmPFC) is known to be associated with volition and motor function but is often overlooked in models of the neural bases of language. In this retrospective study, we reveal a robust statistical association between a rare language profile disproportionately affecting self-generated, but not externally cued, language production and damage to left dmPFC in a large (

Indexed as

aphasiadorsomedial prefrontal cortexdynamic aphasianeurosurgerypre-supplementary motor areatranscortical motor aphasia

Identifiers

PMID40528833

DOI10.1162/nol_a_00166

PMCPMC12170450

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.