Evidence map›Paper›PMID 40528814›Full record

ArticleJournal of agricultural and food chemistry2025

A Lysozyme-Derived Peptide Induces GLP-1 Secretion in Mouse Jejunal Organoids and Modulates Glycemia in Rats.

Santiaga María Vivanco-Maroto, María-Carmen López de Las Hazas, Esperanza Herradón, Rocío Girón, Beatriz Miralles, Nancy Paniagua, Visitación López-Miranda, Alberto Dávalos, Isidra Recio

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Santiaga María Vivanco-MarotoInstituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM, CEI UAM+CSIC), Nicolás Cabrera, 9, Madrid 28049, Spain.
María-Carmen López de Las HazasLaboratory of Epigenetics of Lipid Metabolism, Madrid Institute for Advanced Studies Food (IMDEA Food), CEI UAM + CSIC, Carretera de Canto Blanco, 8, Madrid 28049, Spain.
Esperanza HerradónÁrea de Farmacología, Nutrición y Bromatología, Dpto. C.C. Básicas de la Salud, Facultad de Ciencias de la Salud, Unidad Asociada I+D+i al Instituto de Química Médica (CSIC), Universidad Rey Juan Carlos, Alcorcón 28922, Spain.
Rocío GirónÁrea de Farmacología, Nutrición y Bromatología, Dpto. C.C. Básicas de la Salud, Facultad de Ciencias de la Salud, Unidad Asociada I+D+i al Instituto de Química Médica (CSIC), Universidad Rey Juan Carlos, Alcorcón 28922, Spain.
Beatriz MirallesInstituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM, CEI UAM+CSIC), Nicolás Cabrera, 9, Madrid 28049, Spain.ORCID 0000-0003-4544-9074
Nancy PaniaguaÁrea de Farmacología, Nutrición y Bromatología, Dpto. C.C. Básicas de la Salud, Facultad de Ciencias de la Salud, Unidad Asociada I+D+i al Instituto de Química Médica (CSIC), Universidad Rey Juan Carlos, Alcorcón 28922, Spain.
Visitación López-MirandaÁrea de Farmacología, Nutrición y Bromatología, Dpto. C.C. Básicas de la Salud, Facultad de Ciencias de la Salud, Unidad Asociada I+D+i al Instituto de Química Médica (CSIC), Universidad Rey Juan Carlos, Alcorcón 28922, Spain.
Alberto DávalosLaboratory of Epigenetics of Lipid Metabolism, Madrid Institute for Advanced Studies Food (IMDEA Food), CEI UAM + CSIC, Carretera de Canto Blanco, 8, Madrid 28049, Spain.
Isidra RecioInstituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM, CEI UAM+CSIC), Nicolás Cabrera, 9, Madrid 28049, Spain.ORCID 0000-0003-2973-5329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein digestion products promote the release of incretins, such as GLP-1, which regulate glucose homeostasis. Our previous studies demonstrated that the egg white peptide fraction stimulates GLP-1 secretion in STC-1 cells. Here, the GLP-1 secretion induced by the lysozyme-derived peptide

Indexed as

Blood GlucoseGlucagon-Like Peptide 1JejunumMuramidaseOrganoidsPeptidesAnimalsHumansMaleMiceRatsRats, WistarBlood GlucoseGlucagon-Like Peptide 1MuramidasePeptidesegg white peptidesenteroendocrine cellsGLP-1mouse jejunal organoidstype 2 diabetes

Identifiers

PMID40528814
PMCPMC12232376

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.