ArticleFuture microbiology2025
Microbial isolates and resistance profiles in cerebrospinal fluid cultures: a five-year experience at a tertiary center.
Article in Future microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCentral nervous system infections are a significant global health concern that results in morbidity and mortality. In case of these infections, empirical antibiotic treatment should be initiated according to the microbiological findings of the cerebrospinal fluid (CSF), and the treatment should be rearranged according to the antibiogram results.The study aimed to determine the distribution of meningitis agents and antimicrobial resistance patterns in our hospital.
methodsA total of 17,594 CSF culture samples collected from January 2020 to December 2024 were analyzed retrospectively. The study assessed demographic data, causative microorganisms, and antimicrobial resistance rates.
resultsPositive results were found in 7.3% of CSF culture samples, with 69.1% being gram-positive bacteria and 30.9% gram-negative bacteria. The highest positivity rate was detected in the palliative inpatient clinic (14.8%) despite most cultures being from the neonatal intensive care unit (23.5%). The most common microorganisms were coagulase-negative staphylococci(CoNS) (47.9%) and
conclusionAnalysis of five-year data revealed the types of microorganisms and their antimicrobial resistance in positive CSF cultures. These findings will guide clinicians in promptly choosing the most effective empirical treatment.
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