Evidence map›Paper›PMID 40528497›Full record

ArticleJournal of biochemical and molecular toxicology2025

Synthesis and Biological Assessment of Cyanopyridine-Based 1,3,4-Oxadiazole Derivatives: Anticancer Potential, Antioxidant Activity, Molecular Docking, and DFT Calculations.

Zineddine Zebbiche, Güldeniz Şekerci, Boulebd Houssem, Fatümetüzzehra Küçükbay, Suat Tekin, Hasan Küçükbay, Boudjemaa Boumoud

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biochemical and molecular toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Formal Synthesis ofMolecules (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zineddine ZebbicheLaboratory of Synthesis of Molecules with Biological Interest, Mentouri Constantine University, Constantine, Algeria.ORCID https://orcid.org/0000-0003-0094-3941
Güldeniz ŞekerciPhysiology Department, Faculty of Medicine, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0002-0811-4454
Boulebd HoussemLaboratory of Synthesis of Molecules with Biological Interest, Mentouri Constantine University, Constantine, Algeria.ORCID http://orcid.org/0000-0002-7727-8583
Fatümetüzzehra KüçükbayBasic Pharmaceutical Sciences Department, Faculty of Pharmacy, İnönü University, Malatya, Turkey.ORCID http://orcid.org/0000-0001-7784-4138
Suat TekinPhysiology Department, Faculty of Medicine, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0002-2757-1802
Hasan KüçükbayDepartment of Chemistry, Faculty of Arts and Sciences, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0002-7180-9486
Boudjemaa BoumoudLaboratory of Synthesis of Molecules with Biological Interest, Mentouri Constantine University, Constantine, Algeria.ORCID http://orcid.org/0000-0001-8174-6258

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of six novel cyanopyridine derivatives bearing a 1,3,4-oxadiazole ring have been synthesized and characterized by FTIR,

Indexed as

Antineoplastic AgentsAntioxidantsDensity Functional TheoryMolecular Docking SimulationOxadiazolesPyridinesCaco-2 CellsDNA Topoisomerases, Type IIHumansMCF-7 Cells1,3,4-oxadiazoleAntineoplastic AgentsAntioxidantsDNA Topoisomerases, Type IIOxadiazolesPyridines1,3,4‐oxadiazoleantioxidant activityCaCo‐2cyanopyridineDFT calculationsMCF‐7molecular docking

Identifiers

PMID40528497
PMCPMC12174895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.