Evidence map›Paper›PMID 40528478›Full record

ArticleKidney research and clinical practice2025

Statistical consideration in nephrology research.

Ke Xu, Hakmook Kang

Abstract read
In one paragraph

Article in Kidney research and clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ke XuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Hakmook KangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nephrology research plays an important role in advancing our understanding of kidney disease and improving patient outcomes. However, the complexity of nephrology data and the application of advanced statistical methods present significant challenges. This review highlights key statistical considerations in nephrology research, focusing on common errors such as violations of statistical assumptions, multicollinearity, missing data, overfitting, and the integration of machine learning tools. It emphasizes the importance of applying appropriate statistical approaches to ensure the reliability of study findings. Additionally, the review underscores the need for transparency and reproducibility in nephrology research, particularly the importance of open access to data, code, and study protocols. By utilizing tools like R, RStudio, Git, and GitHub, researchers can integrate their code, results, and data into a transparent workflow, enhancing the reproducibility of their research. This review also presents a practical checklist for promoting reproducible research practices, which can help improve the quality, transparency, and reliability of nephrology studies. This review aims to contribute to the advancement of nephrology research and, ultimately, to support the long-term goal of improving patient care and outcomes.

Indexed as

BiostatisticsChecklistKidney diseasesMachine learningNephrology

Identifiers

PMID40528478
PMCPMC12417584

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.