Evidence map›Paper›PMID 40528296›Full record

ArticleJournal of public health dentistry2025

Racial/Ethnic Differences in the Joint Effect of Edentulism and Diabetes on All-Cause Mortality Risks: A 12-Year Prospective Cohort Analysis.

Xiang Qi, Chenxin Tan, Huabin Luo, Brenda L Plassman, Frank A Sloan, Angela R Kamer, Mark D Schwartz, Bei Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of public health dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiang QiRory Meyers College of Nursing, New York University, New York, New York, USA.ORCID https://orcid.org/0000-0003-3958-8609
Chenxin TanRory Meyers College of Nursing, New York University, New York, New York, USA.
Huabin LuoBrody School of Medicine, East Carolina University, Greenville, North Carolina, USA.ORCID https://orcid.org/0000-0002-5144-3210
Brenda L PlassmanDepartment of Psychiatry and Behavioral Sciences, Duke University, Durham, North Carolina, USA.
Frank A SloanSanford School of Public Policy, Duke University, Durham, North Carolina, USA.
Angela R KamerCollege of Dentistry, New York University, New York, New York, USA.
Mark D SchwartzGrossman School of Medicine, New York University, New York, New York, USA.
Bei WuRory Meyers College of Nursing, New York University, New York, New York, USA.ORCID https://orcid.org/0000-0002-6891-244X

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Rutgers-NYU Center for Asian Health Promotion and EquityP50MD017356 · NIMHD · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI WU, BEI · 2021 to 2025
$11.6M
Resource Center for Alzheimer's and Dementia Research in Asian and Pacific AmericansP30AG083257 · NIA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Cui Yang · 2023 to 2026
$3.5M
Elucidating the Link Between Oral Health and Dementia Subtypes: A Multifaceted Study on the Biological Pathways and Social DeterminantsR01AG089856 · NIA · NEW YORK UNIVERSITY · PI Huabin Luo, Xiang Qi · 2024 to 2026
$2.4M
NIA NIH HHS P30 AG083257NIA NIH HHS R01 AG089856NIA NIH HHS U01 AG009740NIA NIH HHS U01AG009740NIH/National Institute on Aging P30AG083257NIH/National Institute on Aging R01AG089856NIMHD NIH HHS P50 MD017356NIMHD NIH HHS P50MD017356
6 · The paper itself

Abstract

objectivesEdentulism and diabetes mellitus (DM) are frequently seen among older adults. However, the joint effect of edentulism and DM on mortality was understudied. We aim to examine the joint effect of edentulism and DM on all-cause mortality and to what extent the joint effect varies by race/ethnicity.

methodsAnalysis of US Health and Retirement Study (HRS) data (2006-2018) included 11,813 non-Hispanic Whites, 2216 non-Hispanic Blacks, and 1337 Hispanics aged ≥ 50 years old. Mortality data came from the National Death Index or HRS surveys. Edentulism was self-reported and DM was determined by self-reported diagnosis, medication use, or glycosylated hemoglobin. Cox proportional-hazard models with inverse probability treatment weighting were applied.

resultsDuring mean follow-up of 9.6 years, 2874 Whites, 703 Blacks, and 441 Hispanics died. DM was associated with higher mortality across all groups (Whites: HR = 1.43, 95% CI = 1.25-1.64; Blacks: HR = 1.62, 95% CI = 1.28-2.04; Hispanics: HR = 1.46, 95% CI = 1.07-1.99). However, edentulism predicted higher mortality only in Whites (HR = 1.65, 95% CI = 1.51-1.80). Having both conditions showed highest mortality risk in all groups (Whites: HR = 2.31, 95% CI = 1.56-3.42; Blacks: HR = 1.94, 95% CI = 1.45-2.59; Hispanics: HR = 1.77, 95% CI = 1.16-2.70), with a significant additive interaction observed only in Whites (relative excess risk due to interaction = 0.22, p < 0.05).

conclusionsDM and edentulism pose an additive risk for mortality in Whites, and there are racial/ethnic differences in edentulism-related mortality.

Indexed as

Diabetes MellitusEthnicityMouth, EdentulousAgedBlack or African AmericanFemaleHispanic or LatinoHumansMaleMiddle AgedProspective StudiesRisk FactorsUnited StatesWhitedeathdentistryelderlyoral healthoral‐systemic disease(s)tooth loss

Identifiers

PMID40528296
PMCPMC12324938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.