Evidence map›Paper›PMID 40528278›Full record

ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

Posterior Graft Laryngotracheal Reconstruction for Bilateral Vocal Cord Paralysis in a Resource-Limited Setting: Building a Replicable Airway Reconstruction Program in Eldoret, Kenya.

André Isaac, Owen Menach, Gerald Rotich, Amy Callaghan, Daniela M Isaac, Josh Wiedermann, Paula Holinski, Natalie Anton, Evan Propst, Henry Ngoitsi

Abstract read
In one paragraph

Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

André IsaacDivision of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0003-1551-9588
Owen MenachDepartment of ENT-Head and Neck Surgery, Moi Teaching and Referral Hospital, Moi University, Eldoret, Kenya.ORCID 0009-0006-2209-9293
Gerald RotichDepartment of ENT-Head and Neck Surgery, Moi Teaching and Referral Hospital, Moi University, Eldoret, Kenya.
Amy CallaghanDivision of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Alberta, Edmonton, AB, Canada.
Daniela M IsaacDivision of Pediatric Gastroenterology, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0001-9852-4299
Josh WiedermannDivision of Otolaryngology-Head and Neck Surgery, Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, USA.
Paula HolinskiDepartment of Anesthesiology, University of Alberta, Edmonton, AB, Canada.
Natalie AntonDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Evan PropstDepartment of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, ON, Canada.
Henry NgoitsiDepartment of ENT-Head and Neck Surgery, Moi Teaching and Referral Hospital, Moi University, Eldoret, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ImportanceBilateral vocal cord paralysis is a challenging problem to manage in adults, and a known complication of thyroid surgery which is more common in resource-limited settings. Posterior graft laryngotracheal reconstruction is a management option that has not been studied in this population or setting.ObjectiveTo report the surgical outcomes of posterior graft laryngotracheal reconstruction for bilateral vocal cord paralysis in a resource-limited setting, and to evaluate the efficacy of a hybrid system for teaching this technique in Kenya.DesignRetrospective cohort study.SettingTertiary public referral hospital, Eldoret, KenyaParticipantsAdults >18 years with tracheostomy dependence secondary to bilateral vocal cord paralysis after thyroid surgery or other iatrogenesis. The hybrid training program included Kenyan surgeons and surgical trainees.Intervention or ExposuresPosterior graft laryngotracheal reconstruction and hybrid training system included didactic lectures, simulation-based training, case discussion and planning, and live cases.Main Outcomes MeasuresOne-year airway outcomes measured by achievement of tracheostomy decannulation, and self-reported surgeon knowledge and skill acquisition.ResultsTen patients met criteria and were included in the analysis, with mean age 42 years (range 30-62 years) and had been tracheostomy dependent for an average of 6 years (range 1-12 years). Seven (70%) had open reconstruction, and 3 (30%) had endoscopic reconstruction. All were decannulated and remained tracheostomy-free at 1 year. Three surgeons and 7 trainees participated in the hybrid teaching methods. All reported increased comfort in laryngotracheal reconstruction, with all 3 surgeons reporting comfort performing the surgeries independently.ConclusionPosterior graft laryngotracheal reconstruction shows promise as a potential method of treating bilateral vocal cord paralysis and achieving decannulation in a resource-limited setting.RelevanceThe methods reported in this study lend themselves to replication and expansion to other similar settings. The authors plan to replicate this work in other centers in East Africa.

Indexed as

LaryngoplastyLarynxPlastic Surgery ProceduresTracheaVocal Cord ParalysisAdultFemaleHumansKenyaMaleMiddle AgedResource-Limited SettingsTracheostomyTreatment Outcomeairway stenosis/reconstructionbronchoesophagologycomprehensive otolaryngologymedical educationvocal fold paralysis/paresis

Identifiers

PMID40528278
PMCPMC12174730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.