Evidence map›Paper›PMID 40528223›Full record

ArticleGeneral thoracic and cardiovascular surgery cases2025

Unsuccessful aortic fenestration for aortic dissection complicated with mesenteric malperfusion analyzed using computational fluid dynamics: a case report.

Shoki Iwanaga, Naoyuki Kimura, Shuta Imada, Mutsumi Mizoguchi, Mamoru Arakawa, Hirohiko Akutsu, Koji Kawahito, Masanori Nakamura

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Article in General thoracic and cardiovascular surgery cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Shoki IwanagaDepartment of Surgery, Division of Cardiovascular Surgery, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, 329-0498, Japan.
Naoyuki KimuraDepartment of Surgery, Division of Cardiovascular Surgery, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, 329-0498, Japan. kimura-n@omiya.jichi.ac.jp.ORCID http://orcid.org/0000-0003-2618-6934
Shuta ImadaDepartment of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Gokiso, Showa, Nagoya, 466-8555, Japan.
Mutsumi MizoguchiDepartment of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Gokiso, Showa, Nagoya, 466-8555, Japan.
Mamoru ArakawaDepartment of Surgery, Division of Cardiovascular Surgery, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, 329-0498, Japan.
Hirohiko AkutsuDepartment of Surgery, Division of Cardiovascular Surgery, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, 329-0498, Japan.
Koji KawahitoDepartment of Surgery, Division of Cardiovascular Surgery, Jichi Medical University, Yakushiji 3311-1, Shimotsuke, 329-0498, Japan.
Masanori NakamuraDepartment of Electrical and Mechanical Engineering, Nagoya Institute of Technology, Gokiso, Showa, Nagoya, 466-8555, Japan. masanorin@nitech.ac.jp.

Funding

JSPS KAKENHI Grant 21K08828
6 · The paper itself

Abstract

backgroundWe report a computational fluid dynamics (CFD)-based analysis of an unsuccessful open fenestration for aortic dissection with mesenteric malperfusion. CASE PRESENTATION: A 75-year-old male was admitted for acute type B aortic dissection complicated by mesenteric malperfusion. He had a concomitant infrarenal abdominal aneurysm, prompting surgical infrarenal fenestration. Intraoperatively, the proximal intimal flap was resected near the renal arteries, and the aneurysm was replaced with a prosthetic graft. Despite the intervention, mesenteric malperfusion worsened, requiring additional endovascular aortic repair. CFD analysis revealed persistent false lumen flow and true lumen compression due to a large entry tear and residual proximal anastomotic stenosis.

conclusionCFD analysis suggests that a large entry tear and residual stenosis from insufficient fenestration may result in inadequate false lumen depressurization.

Indexed as

Aortic dissectionAortic fenestrationComputational fluid dynamicsMesenteric malperfusion

Identifiers

PMID40528223
PMCPMC12175397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.