Evidence map›Paper›PMID 40528184›Full record

ReviewThe journal of headache and pain2025

Emerging treatments for chronic neuropathic pain from a cross-disease perspective: developments and applications of nanomaterials.

Rui Sun, Xiaoqin Zhang, Tao Dou, Zhiyi Xiao, Xiaoran Deng

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of headache and pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rui SunJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, 221004, China.
Xiaoqin ZhangJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, 221004, China.
Tao DouJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, 221004, China.
Zhiyi XiaoJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, 221004, China.
Xiaoran DengJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, 221004, China. xrdeng@xzhmu.edu.cn.

Funding

National Natural Science Foundation of China 52302356Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX24_3111Xuzhou Basic Research Program Funds KC22008Xuzhou Medical University Youth Science and Technology Innovation Team Program TD202203
6 · The paper itself

Abstract

Chronic neuropathic pain (CNP) results from disease or damage within the somatosensory nervous system. It represents a prevalent and challenging form of chronic pain that exerts a severe impact on patients' quality of life. This review aims to synthesize and highlight the current understanding of the mechanisms underlying CNP, as well as the evolving therapeutic landscape. With advancements in research, an increasing number of analgesic targets specific to various disease types are being developed, alongside the emergence of novel nanomaterials for treating chronic pain. In this review, we systematically summarize the applications and potential mechanisms of nanomaterials in treating CNP induced by various diseases, providing new insights for both fundamental research and clinical management of CNP.

Indexed as

AnalgesicsChronic PainNanostructuresNeuralgiaAnimalsHumansAnalgesicsChronic painClinical disease modelsCNPNanodrug delivery systemsNanomaterials

Identifiers

PMID40528184
PMCPMC12172365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.