Evidence map›Paper›PMID 40527910›Full record

ArticleMicrosystems & nanoengineering2025

Battery-free and self-propelled bionic microneedle system for chemically controlled on-demand drug delivery.

Yuyu Tan, Cao Tan, Mengli Luo, Yuxue Miao, Jiaoli Wang, Xinlin Wang, Zhu Chen, Lelun Jiang, Jian Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microsystems & nanoengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuyu TanHunan Province Key Laboratory for Ultra-Fast Micro/Nano Technology and Advanced Laser Manufacture, School of Electrical Engineering, University of South China, Hengyang, 421001, China.
Cao TanHunan Province Key Laboratory for Ultra-Fast Micro/Nano Technology and Advanced Laser Manufacture, School of Electrical Engineering, University of South China, Hengyang, 421001, China.
Mengli LuoHunan Province Key Laboratory for Ultra-Fast Micro/Nano Technology and Advanced Laser Manufacture, School of Electrical Engineering, University of South China, Hengyang, 421001, China.
Yuxue MiaoHunan Province Key Laboratory for Ultra-Fast Micro/Nano Technology and Advanced Laser Manufacture, School of Electrical Engineering, University of South China, Hengyang, 421001, China.
Jiaoli WangHunan Province Key Laboratory for Ultra-Fast Micro/Nano Technology and Advanced Laser Manufacture, School of Electrical Engineering, University of South China, Hengyang, 421001, China.
Xinlin WangHunan Province Key Laboratory for Ultra-Fast Micro/Nano Technology and Advanced Laser Manufacture, School of Electrical Engineering, University of South China, Hengyang, 421001, China.
Zhu ChenInstitute for Future Sciences, University of South China, Changsha, 410008, China.
Lelun JiangGuangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, 518057, China.ORCID http://orcid.org/0000-0002-5530-3266
Jian YangHunan Province Key Laboratory for Ultra-Fast Micro/Nano Technology and Advanced Laser Manufacture, School of Electrical Engineering, University of South China, Hengyang, 421001, China. jensenwin@usc.edu.cn.ORCID http://orcid.org/0009-0001-9227-0539

Funding

National Natural Science Foundation of China (National Science Foundation of China) 51975597National Natural Science Foundation of China (National Science Foundation of China) 82402492
6 · The paper itself

Abstract

Developing a promising on-demand controllable microneedle drug delivery system could provide stronger self-control and precision delivery of a large payload capacity. Nevertheless, the efficacy of existing systems has been constrained by limitations in the therapeutic payload capacity and slow diffusion of molecules, as well as the necessity for external resource configurations. Drawing inspiration from the multidimensional biomimetic strategies observed in the material properties and functional mechanisms of the bombardier beetle's defensive secretion system, a battery-free and self-propelled biomimetic microneedle system (BSBMs) is proposed for improving therapeutic outcomes and enabling controlled, on-demand drug delivery. The self-powered microneedle delivery platform fully emulates the structure and spray mechanism of bombardier, employing Pt nanoparticles and H

Identifiers

PMID40527910
PMCPMC12174333

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.