Evidence map›Paper›PMID 40527908›Full record

ArticleScientific data2025

A single-cell plume transcriptome atlas of the cold-seep tubeworm Paraescarpia echinospica.

Yingying Zhang, Xianghui Zhang, Nannan Zhang, Hongxi Chen, Jie Ma, Zhen Cui, Qianyue Ji, Ximeng Dong, Yunlu Xiao, Zhe Zhang and 5 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yingying Zhang *BGI Research, Sanya, 572025, China.
Xianghui Zhang *BGI Research, Sanya, 572025, China.
Nannan Zhang *BGI Research, Sanya, 572025, China.
Hongxi Chen *BGI Research, Sanya, 572025, China.
Jie MaInstitute of Deep-sea Science and Engineering, Chinese Academy of Sciences, Sanya, 572000, China.
Zhen CuiBGI Research, Sanya, 572025, China.
Qianyue JiMGI Tech, Shenzhen, 518083, China.
Ximeng DongMGI Tech, Shenzhen, 518083, China.
Yunlu XiaoInstitute of Deep-sea Science and Engineering, Chinese Academy of Sciences, Sanya, 572000, China.
Zhe ZhangMGI Tech, Shenzhen, 518083, China.
Guangyi FanQingdao Key Laboratory of Marine Genomics, BGI Research, Qingdao, 266555, China.ORCID 0000-0001-7365-1590
Weijia ZhangInstitute of Deep-sea Science and Engineering, Chinese Academy of Sciences, Sanya, 572000, China.
Shanshan LiuBGI Research, Shenzhen, 518083, China.
Haibin ZhangInstitute of Deep-sea Science and Engineering, Chinese Academy of Sciences, Sanya, 572000, China. hzhang@idsse.ac.cn.
Liang MengBGI Research, Sanya, 572025, China. mengliang1@genomics.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vestimentiferan tubeworms are representative species in deep-sea chemosynthetic ecosystems. Unlike most animals, these invertebrates lack mouths and digestive systems. Instead, their plumes function as the primary organ for direct metabolic exchange with the environment. Here, we present the single-cell transcriptome atlas of the Paraescarpia echinospica plume, offering single-cell resolution analysis for a deep-sea tubeworm. Our analysis revealed six cell clusters, namely hemocytes, proliferative cells, muscle cells, epithelial cells, nerve1 cells, and nerve2 cells, and we further characterized genes associated with immunity and transport. These findings establish a crucial foundation for future single-cell studies of tubeworms.

Indexed as

PolychaetaTranscriptomeAnimalsSingle-Cell Analysis

Identifiers

PMID40527908
PMCPMC12174347

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None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.