Evidence map›Paper›PMID 40527888›Full record

ArticleBlood cancer journal2025

A phase 2 study of Daratumumab with Thalidomide and dexamethasone in relapsed and/or Refractory Myeloma (RRMM).

Chandramouli Nagarajan, Wei-Ying Jen, Melissa Ooi, Sanjay De Mel, Cinnie Soekojo, Sung Soo Yoon, Melinda Tan, Yunxin Chen, Xinhua Li, Yogesh Pokharkar and 6 more

Registry-linked trialAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03153036, which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03153036 no registry record found
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Chandramouli Nagarajan *Department of Haematology, Singapore General Hospital, Singapore, Singapore.
Wei-Ying Jen *Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.ORCID http://orcid.org/0000-0002-9339-3362
Melissa OoiDepartment of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.ORCID http://orcid.org/0000-0002-7392-0655
Sanjay De MelDepartment of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.ORCID http://orcid.org/0000-0002-8881-3537
Cinnie SoekojoDepartment of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.
Sung Soo YoonSeoul National University Hospital, Seoul, South Korea.ORCID http://orcid.org/0000-0002-2302-3825
Melinda TanDepartment of Haematology, Singapore General Hospital, Singapore, Singapore.
Yunxin ChenDepartment of Haematology, Singapore General Hospital, Singapore, Singapore.ORCID http://orcid.org/0000-0001-9039-3474
Xinhua LiSingapore Clinical Research Institute, Singapore, Singapore.
Yogesh PokharkarSingapore Clinical Research Institute, Singapore, Singapore.
Shi Ning ThamDepartment of Haematology, Singapore General Hospital, Singapore, Singapore.
Nur Shahidah Binte HashimDepartment of Haematology, Singapore General Hospital, Singapore, Singapore.
Neha AwasthiSingapore Clinical Research Institute, Singapore, Singapore.
Sarah M BurkillSingapore Clinical Research Institute, Singapore, Singapore.
Brian DurieCedars-Sinai Medical Center, Los Angeles, USA.
Wee Joo ChngDepartment of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore. mdccwj@nus.edu.sg.ORCID http://orcid.org/0000-0003-2578-8335

Funding

Janssen Pharmaceuticals (Janssen Pharmaceuticals, Inc.) N/A
6 · The paper itself

Abstract

trial registrationNCT03153036.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsMultiple MyelomaAdultAgedAntibodies, MonoclonalClinical Trials, Phase II as TopicDexamethasoneFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalRecurrenceThalidomideTreatment OutcomeAntibodies, MonoclonaldaratumumabDexamethasoneThalidomide

Identifiers

PMID40527888
PMCPMC12174351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.