Evidence map›Paper›PMID 40527789›Full record

Observational studyMedicine2025

Is age a determinant in cervical cancer screening in women aged 18 to 29?: An observational study.

Ayça K Küçükyurt, Nil Atakul, Selma Atiye Kolcu, Ayşet Jane Özcan, Narmin Abdullazade

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ayça K KüçükyurtDepartment of Obstetrics and Gynecology, İstanbul Training and Research Hospital, İstanbul, Turkey.ORCID 0000-0003-4959-3663
Nil AtakulDepartment of Obstetrics and Gynecology, İstanbul Training and Research Hospital, İstanbul, Turkey.ORCID 0000-0003-3874-8797
Selma Atiye KolcuDepartment of Obstetrics and Gynecology, İstanbul Training and Research Hospital, İstanbul, Turkey.ORCID 0000-0002-6849-0136
Ayşet Jane ÖzcanDepartment of Obstetrics and Gynecology, Altinbas University Faculty of Medicine, İstanbul, Turkey.ORCID 0000-0001-5785-5729
Narmin AbdullazadeDepartment of Obstetrics and Gynecology, İstanbul Training and Research Hospital, İstanbul, Turkey.ORCID 0009-0007-6405-7478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to analyze the impact of aging on cervical cancer screening among women aged 20 to 29. Specifically, it examines the occurrence of abnormal histological results and Cervical Intraepithelial Neoplasia (CIN) (+) lesions within these age groups. We retrospectively analyzed women aged 18 to 29 (<30) who underwent cervical cancer screening through cytology between 2014 and 2024. A total of 842 women who visited the gynecology outpatient clinic were included, and their Pap smear, colposcopy, and loop electrosurgical excision procedure/conization results were reviewed. Patients were divided into 2 age groups (18-25 and 26-29) for comparative analysis. Among the 842 women who underwent cytological evaluation: 744 (88.4%) had normal results, 51 (6.1%) were diagnosed with atypical squamous cells of undetermined significance (ASC-US), 31 (3.7%) with low-grade squamous intraepithelial lesion (LSIL), 8 (1.0%) with atypical squamous cells - cannot exclude high-grade lesion (ASC-H), 4 (0.5%) with High-Grade Squamous Intraepithelial Lesion (HSIL), and 4 (0.5%) with Atypical Glandular Cells (AGC). HPV (Human Papillomavirus) testing was performed on 75 women, and 40 (53.3%) tested positive for HPV. Colposcopy was conducted on 53 women, revealing CIN + lesions in 38 cases, while conization confirmed CIN + lesions in 23 cases. Colposcopy results revealed the presence of CIN 1, CIN 2, and CIN 3 lesions in both age groups. However, CIN 3 lesions were observed less frequently in the > 26 age group. Similarly, conization results showed a lower incidence of CIN 3 lesions in women older than 26. Women aged 18 to 25 had a higher likelihood of CIN 3 diagnosis. These findings emphasize the importance of considering age in the diagnosis of CIN (+) lesions during cervical cancer screening.

Indexed as

Early Detection of CancerUterine Cervical DysplasiaUterine Cervical NeoplasmsAdolescentAdultAge FactorsColposcopyFemaleHumansPapanicolaou TestPapillomavirus InfectionsRetrospective StudiesVaginal SmearsYoung Adultcervical cancercolposcopycytologyHPVsmear

Identifiers

PMID40527789
PMCPMC12173301

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.