ArticleMedicine2025
Concurrent hepatitis and anterior uveitis in an immunocompetent patient with secondary syphilis: A case report.
Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
rationaleSyphilis, a sexually transmitted infection caused by Treponema pallidum, is primarily spread through sexual contact and can lead to severe systemic complications if untreated. PATIENT CONCERNS: A 42-year-old immunocompetent male presented with a nonpruritic papulosquamous rash sparing the palms and soles, which progressed to anterior uveitis and hepatitis. DIAGNOSES: Diagnosis was confirmed by positive rapid plasma reagin and T pallidum hemagglutination assay, alongside histopathological evidence of granulomatous hepatitis on liver biopsy and slit-lamp findings consistent with anterior uveitis.
interventionsThe patient was hospitalized and treated with intravenous aqueous penicillin G (3 million units every 4 hours for 14 days). OUTCOMES: To our knowledge, this represents the first reported case in Saudi Arabia of secondary syphilis manifesting concurrently with anterior uveitis and hepatitis in an immunocompetent host. LESSONS: The study underscores the importance of considering syphilis in atypical presentations to ensure timely diagnosis and management.
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