Moving from dementia risk disclosure to return of individual research results: a bioethics perspective.

Bilal Irfan, Kelly Bakulski, Jonathan Reader, Annalise Rahman-Filipiak

Abstract read

In one paragraph

Article in The lancet. Healthy longevity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Defining healthy longevity and dementia prevention campaigns have been tied to the ability to work.Journal of Alzheimer's disease reports
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bilal IrfanCenter for Bioethics, Harvard Medical School, Boston, MA 02115, USA; Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA; Michigan Alzheimer's Disease Center, Ann Arbor, MI, USA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA. Electronic address: birfan@umich.edu.

Kelly BakulskiMichigan Alzheimer's Disease Center, Ann Arbor, MI, USA; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.

Jonathan ReaderMichigan Alzheimer's Disease Center, Ann Arbor, MI, USA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA.

Annalise Rahman-FilipiakMichigan Alzheimer's Disease Center, Ann Arbor, MI, USA; Research Program on Cognition and Neuromodulation Based Interventions, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.

Funding

Research Education ComponentP30AG072931 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Scott ROBERTS · 2021 to 2026

$26.5M

DNA methylation in context: Racial inequities in social adversity and vulnerability to the health impact of air pollution - Diversity Supplement (Fike)R01AG074887 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HICKEN, MARGARET TAKAKO · 2021 to 2025

$3.4M

Behavioral Change Following Culturally-Informed Biomarker Disclosure in Alzheimer’s DiseaseK23AG070044 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAHMAN-FILIPIAK, ANNALISE · 2021 to 2025

$914k

NIA NIH HHS K23 AG070044NIA NIH HHS P30 AG072931NIA NIH HHS R01 AG074887

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40527327

DOI10.1016/j.lanhl.2025.100723

PMCPMC12255516

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.