Evidence map›Paper›PMID 40527298›Full record

ArticleThe American journal of tropical medicine and hygiene2025

Intrathoracic Echinococcosis: A 5-Year, Single-Center Experience.

Raffaella Lissandrin, Ambra Vola, Matilde Pelizzola, Federico Scopis, Stefano Meda, Cristiano Primiceri, Gianluca D'Alessandro, Tommaso Manciulli, Marcello Maestri, Enrico Brunetti and 1 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Modern Surgical Approaches to Pulmonary Hydatidosis.The American journal of tropical medicine and hygiene · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Raffaella LissandrinDivision of Infectious Diseases I, IRCCS San Matteo Hospital Foundation, Pavia, Italy.
Ambra VolaMicrobiology and Virology Unit, IRCCS San Matteo Hospital Foundation, Pavia, Italy.
Matilde PelizzolaDepartment of Clinical, Surgical Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy.
Federico ScopisDivision of Thoracic Surgery, AOU San Luigi Gonzaga, Torino, Italy.
Stefano MedaDivision of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy.
Cristiano PrimiceriDivision of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy.
Gianluca D'AlessandroDepartment of Clinical, Surgical Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy.
Tommaso ManciulliDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Marcello MaestriDepartment of General Surgery 1, IRCCS San Matteo Hospital Foundation, Pavia, Italy.
Enrico BrunettiDivision of Infectious Diseases I, IRCCS San Matteo Hospital Foundation, Pavia, Italy.
Pietro RinaldiDivision of Thoracic Surgery, SS Antonio, Biagio and Cesare Arrigo Hospital, Alessandria, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cystic echinococcosis (CE) is caused by the larval forms of Echinococcus granulosus s.l. species complex that mainly affect the liver, with lung as the second most frequent location. We describe our experience with surgical treatment of lung CE, emphasizing the need for the least invasive approach when possible. Patients with intrathoracic CE who accessed our center from January 2019 to November 2023 were reviewed. Twenty-two patients, 12 males (54.5%), mean age 35 years, range 9-60, were treated. Eight patients (36.4%) had only lung involvement, seven (31.8%) had both liver and lung involvement, and seven (31.8%) had other locations. Thoracic surgery was required for large dimensions or pain (six each), hemoptysis (four each), skin fistulization and pericardial involvement (two each), and infection and emission of parasitic material by cough (one). A minimally invasive video-assisted thoracic surgery approach was used for 12 (54.5%) patients, whereas 10 underwent anterior thoracotomy. Three patients underwent sequential lung and hepatic surgery in a single session, one with myocardial wall involvement underwent thoracic and cardiac surgery in a single session. All patients received albendazole before and during surgery. There was no operative and postoperative mortality. The mean follow-up was 11.5 months (range 1-30). Patients with intrathoracic CE may present with acute and even life-threatening symptoms and should be managed preferably with tissue-sparing surgery by a multidisciplinary team in a referral center.

Indexed as

EchinococcosisEchinococcosis, PulmonaryAdolescentAdultAlbendazoleAnimalsChildEchinococcus granulosusFemaleHumansLungMaleMiddle AgedRetrospective StudiesThoracic Surgery, Video-AssistedThoracotomyAlbendazole

Identifiers

PMID40527298
PMCPMC12360070

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.