Evidence map›Paper›PMID 40527261›Full record

ArticleThe Science of the total environment2025

Children's environmental and occupational exposures to pesticides in low- and middle-income countries rural areas - an elephant in the room.

Rafael Buralli, Siti Nurshahida Nazli, Leonel Cordoba, Lesliam Quiros-Alcala, Carly Hyland, María Teresa Muñoz-Quezada, Paulina Farías, Alexis J Handal

Abstract read
In one paragraph

Article in The Science of the total environment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rafael BuralliDepartment of Policy, Management and Health, School of Public Health, University of São Paulo, São Paulo, SP, Brazil. Electronic address: rafael.buralli@gmail.com.
Siti Nurshahida NazliUniversity of Queensland, Child Health Research Centre, South Brisbane, QLD, Australia; Department of Environmental Health, Faculty of Health Sciences, Universiti Teknologi MARA, Pulau Pinang, Malaysia.
Leonel CordobaGeography School, National University, Costa Rica.
Lesliam Quiros-AlcalaDepartment of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.
Carly HylandUniversity of California Agriculture and Natural Resources, UC Berkeley Environmental Health Sciences, Berkeley, United States.
María Teresa Muñoz-QuezadaSchool of Public Health, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Paulina FaríasInstituto Nacional de Salud Pública, Mexico.
Alexis J HandalDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, United States.

Funding

Translation CoreP2CES033433 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jill E Johnston · 2022 to 2026
$4.9M
NIEHS NIH HHS P2C ES033433
6 · The paper itself

Abstract

In rural areas of Low- and Middle-Income Countries, children are regularly exposed to pesticides through various environmental, para-occupational, and occupational pathways, often connected to family-based agricultural activities. Work and living spaces are commonly intertwined, increasing the likelihood of unintentional pesticide exposure among children, including before birth. This commentary explores how such wide-spread exposures to these pervasive chemicals occur - even before birth, and affect critical aspects of child health and development through life. Using the history of Zeca, a child living in rural Brazil whose asthma worsens due to pesticide applications near his home, this discussion paper illustrates how this critical issue is deeply embedded in daily life in many agricultural communities. However, these risks are frequently overlooked in clinical assessments, health surveillance, and policy responses. We discuss how broader structural conditions contribute to children's exposure to pesticides, including poverty, lack of healthcare access, weak surveillance or enforcement of occupational and environmental protections, and the chemical colonialism. These patterns reflect entrenched social and environmental injustices that disproportionately affect rural children. Thus, we call for a coordinated and systemic response involving stronger regulation, enhanced health surveillance and management, support for safer and more sustainable agricultural practices, and the inclusion of rural communities in decision-making processes. The protection of children from harmful pesticide exposure must be recognized as a public health priority and a matter of social and environmental justice.

Indexed as

Environmental ExposureOccupational ExposurePesticidesAgricultureBrazilChildDeveloping CountriesHumansRural PopulationPesticides

Identifiers

PMID40527261
PMCPMC12478522

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.