Evidence map›Paper›PMID 40526738›Full record

SynthesisPloS one2025

The effect of cognitive behavioural therapy on pain and disability in chronic non-specific low back pain: An overview of systematic reviews.

Tiffany Leung, Mei Ken Low, Pei Chi Yao, Ana-Catarina Pinho-Gomes

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tiffany LeungInstitute of Epidemiology and Health Care, University College London, London, United Kingdom.ORCID 0009-0001-7140-6177
Mei Ken LowInstitute of Ophthalmology, University College London, London, United Kingdom.ORCID 0000-0002-1880-0335
Pei Chi YaoInstitute of Epidemiology and Health Care, University College London, London, United Kingdom.
Ana-Catarina Pinho-GomesInstitute for Global Health, University College London, London, United Kingdom.ORCID 0000-0001-9895-1493

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow back pain (LBP) is experienced by most people at least once in their lifetime and is the leading cause of disability worldwide. Cognitive behavioural therapy (CBT) is a non-invasive method used to manage chronic non-specific low back pain (CNSLBP) and contains less adverse effects than analgesic medications.

aimsTo determine the efficacy of interventions incorporating CBT on reducing pain intensity and physical disability in CNSLBP.

methodsAn overview of reviews without meta-analysis was conducted. Four electronic databases (MEDLINE, Embase, Cochrane Library and PsycINFO) were searched. Adults aged 18 or above with CNSLBP were included. AMSTAR 2 was used to assess risk of bias of included systematic reviews and data synthesis was conducted via vote counting methods.

resultsTen systematic reviews were included. Results showed that CBT is more effective in reducing pain and disability compared to waiting list/usual care (WL/UC). CBT in conjunction with other active treatments (AT) are also more effective than some standalone AT such as physiotherapy and exercise, but less effective than surgery.

conclusionCBT has some effect in reducing pain and disability, however, it may not be more effective than other treatments. The quality of evidence was low for most outcomes as there was high risk of bias and heterogeneity between studies. Future research could evaluate specific therapies such as acceptance and commitment therapy (ACT) and mindfulness-based cognitive therapy (MBCT), as these treatments lacked primary studies. There is no recognised standard for conducting CBT, and further research could determine the most effective duration, mode of delivery (e.g., online, group-based) and intensity of CBT.

Indexed as

Chronic PainCognitive Behavioral TherapyLow Back PainPersons with DisabilitiesHumansPain ManagementSystematic Reviews as TopicTreatment Outcome

Identifiers

PMID40526738
PMCPMC12173195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.