Evidence map›Paper›PMID 40526579›Full record

Observational studyDeutsches Arzteblatt international2025

Decline in Incidence and Prevalence of Dementia: An Analysis of Outpatient Claims Data.

Bernhard Michalowsky, Wolfgang Hoffmann, Steffi Riedel-Heller, Claudia Kohring, Stefan Teipel, Manas K Akmatov, Jens Bohlken, Jakob Holstiege

Abstract readObservational Study
In one paragraph

Observational study in Deutsches Arzteblatt international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. In Reply.Deutsches Arzteblatt international · 2025
    Article
  5. Surprising Results.Deutsches Arzteblatt international · 2025
    Article
  6. A Surprising Decline in the Incidence of Dementia.Deutsches Arzteblatt international · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bernhard MichalowskyGerman Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany, Patient-reported Outcomes & Health Economics Research, Greifswald, Germany, and McMaster University, Health Research Methods, Evidence and Impact, Hamilton, Canada; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Germany, AG Translationale Versorgungsforschung, Greifswald, und Institut für Community Medicine, Versorgungsepidemiologie und Community Health, Universitätsmedizin Greifswald; Faculty of Medicine, Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany; Central Research Institute of Ambulatory Health Care in Germany, Berlin; Clinic and Polyclinic for Psychosomatics and Psychotherapeutic Medicine, Section for Gerontopsychosomatics and Dementia, Rostock University Medical Centre; German Centre for Neurodegenerative Diseases (DZNE) Rostock/Greifswald, Clinical Dementia Research Group, Rostock, Gemany.
Wolfgang Hoffmann
Steffi Riedel-Heller
Claudia Kohring
Stefan Teipel
Manas K Akmatov
Jens Bohlken
Jakob Holstiege

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn increase in dementia is expected worldwide because of the aging of the population. However, recent studies suggest that its incidence is declining.

methodsClaims data from the German statutory health insurance system (covering 88% of the population) were analyzed for the years 2015 to 2022. Insurees aged 65 and older were included for whom a confirmed diagnosis of dementia was documented in at least two of four consecutive quarters. The incidence and prevalence of dementia were calculated and standardized by age and sex.

resultsThe incidence of dementia declined by 26% percent (95% confidence interval: -26.2; -25.3), from 2020 per 100 000 insured individuals in 2015 to 1500 per 100 000 in 2022. Over the same period, its prevalence fell by 18% [-18.6; -18.2], from 10 380 to 8470 per 100 000 insured individuals. These trends were more pronounced in younger age groups and in women and were particularly evident in primary care practices. The number of individuals with a documented diagnosis of dementia fell from 1.56 million in 2015 to 1.43 million in 2022, corresponding to a decline by 8.4% [-8.5; -8.3]. Over the same period, the number of people with a diagnosis of mild cognitive impairment (MCI) increased by 62%, albeit from a very low initial level.

conclusionDespite the aging of the population, the incidence and prevalence of diagnosed dementia in German primary care practices are declining. Further analysis is needed to determine whether this is due to a lower individual risk of dementia, changes in diagnostic behavior, or structural factors, such as a shift to specialized memory clinics.

Indexed as

DementiaOutpatientsAgedAged, 80 and overAge DistributionFemaleGermanyHumansIncidenceInsurance Claim ReviewMalePrevalenceSex Distribution

Identifiers

PMID40526579
PMCPMC12571392

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.