ArticleIEEE transactions on medical imaging2025
Robotic Optical Coherence Tomography With Expanded Three-Dimensional Field-of-View Using Point-Cloud-Based Volumetric Montaging.
Article in IEEE transactions on medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Autonomous robotic alignment and dynamic illumination control of an ophthalmic slit lamp forJournal of biomedical optics · 2026Article
- Intensity Variance-Guided Automated Robotic Optical Coherence Tomography System for Ophthalmic Applications.Journal of biophotonics · 2026Article
- Article
- Machine-Learning-Based Automated Schlemm's Canal Volumetric Segmentation for Optical Coherence Tomography.Chemical & biomedical imaging · 2026Article
- Cholinergic Improvement of Low-Flow Segmental Aqueous Humor Outflow in Humans.Ophthalmology science · 2026Article
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Authors and funding
10 authors.
Funding
Abstract
Imaging complex, non-planar anatomies with optical coherence tomography (OCT) is limited by the optical field of view (FOV) in a single volumetric acquisition. Combining linear mechanical translation with OCT extends the FOV but suffers from inflexibility in imaging non-planar anatomies. We report the robotic OCT to fill this gap. To address challenges in volumetric reconstruction associated with the robotic movement accuracy being two orders of magnitudes worse than OCT imaging resolution, we developed a volumetric montaging algorithm. To test the robotic OCT, we imaged the entire circumferential aqueous humor outflow pathway, whose imaging has the potential to customize glaucoma surgeries but is typically constrained by the FOV in mice in vivo. We acquired volumetric OCT data at different robotic poses and reconstructed the entire anterior segment of the eye. From the segmented Schlemm's canal volume, we showed its circumferentially heterogeneous morphology; we also revealed a segmental nature in the circumferential distribution of collector channels with spatial features as small as a few micrometers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.