ArticleHernia : the journal of hernias and abdominal wall surgery2025
Acute inflammation triggered by two lightweight hernia meshes: a comparative in vitro and retrospective cohort study.
Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Mapping the Prosthetic-Host Interactome: From Systemic Inflammation to Biological Integration in Mesh-Enhanced Therapies METs-A Scoping Review.International journal of molecular sciences · 2026Article
- Chronic Groin Pain After Hernia Surgery: What Are We Missing?Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRetro-muscular mesh augmentation is standard for repairing abdominal incisional or larger primary hernia. A wide variety of meshes with diverse properties are available. The knowledge on the immune-modulating effects of meshes is, however, insufficient. This study investigates the impact of two widely used lightweight meshes, ULTRAPRO
methodsHuman THP-1 cell-derived macrophages were cultured in absence and presence of ULTRAPRO
resultsIn the presence of ULTRAPRO
conclusionMeshes exhibit distinct immune-modulating effects on macrophages, leading to differential activation that may influence foreign-body reaction and systemic inflammation. These immune responses potentially impact clinical outcomes and recurrence after hernia repair. This study underscores the need for comparative prospective, randomized-controlled trials to further evaluate the clinical relevance of mesh-specific immunological effects.
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