Evidence map›Paper›PMID 40526207›Full record

Observational studyJapanese journal of ophthalmology2025

Relationship between acceleration of axial elongation and ocular biometry in schoolchildren.

Takehiro Yamashita, Hiroto Terasaki, Takuto Hamada, Ryo Asaoka, Naoya Yoshihara, Naoko Kakiuchi, Taiji Sakamoto

Abstract readObservational Study
In one paragraph

Observational study in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Takehiro YamashitaDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Hiroto TerasakiDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. teracchi@m2.kufm.kagoshima-u.ac.jp.
Takuto HamadaDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Ryo AsaokaDepartment of Ophthalmology, Seirei Hamamatsu General Hospital, Shizuoka, Japan.
Naoya YoshiharaDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Naoko KakiuchiDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Taiji SakamotoDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Funding

Japan Society for the Promotion of Science 21H03095Japan Society for the Promotion of Science 21K09704Japan Society for the Promotion of Science 24K12746
6 · The paper itself

Abstract

purposeThe speed of axial elongation typically slows during the growth phase; however, in some eyes, it accelerates, leading to myopia progression during school age. This study examined the association between ocular biometrics and the acceleration of axial elongation (AAE) in children. STUDY

designLongitudinal, prospective, observational study

methodsThis cohort study included 67 right eyes of elementary school children, tracked over six years (from ages 8.5 to 14.5). Annual measurements were conducted for optical axial length, anterior chamber depth, and lens thickness. Yearly axial elongation was calculated for each time period, and AAE was estimated using regression analysis coefficients. Spearman's correlation was used to evaluate the association between AAE and ocular biometric parameters measured in the first year.

resultsThe average axial length in the initial year was 23.37 ± 0.89 mm. By the sixth year, the mean axial elongation reached 1.50 ± 0.49 mm, while the average AAE was recorded as -0.015 ± 0.048. AAE was significantly correlated with first-year axial length (r = - 0.40, p < 0.001), anterior chamber depth (r = 0.33, p = 0.007), and lens thickness (r = - 0.42, p < 0.001).

conclusionSome eyes with hyperopic ocular biometry at 8.5 years of age exhibited accelerated axial elongation during school age. Future research on myopia should consider both acceleration and axial elongation.

Indexed as

Axial Length, EyeBiometryMyopiaRefraction, OcularAdolescentAnterior ChamberChildDisease ProgressionFemaleFollow-Up StudiesHumansLens, CrystallineMaleProspective StudiesAnterior chamber depthAxial elongationAxial lengthOcular enlargementSchool myopia

Identifiers

PMID40526207
PMCPMC12594635

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.