Evidence map›Paper›PMID 40526128›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Enhanced vascular inflammation in patients with advanced prostate cancer receiving hormone therapy.

Holger Einspieler, Dina Muin, Ilva Kristiana Langrate, Stefan Schmitl, Clemens P Spielvogel, Barbara J Fueger, Xiang Li, Gero Kramer, Shahrokh F Shariat, Marcus Hacker and 1 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Holger Einspieler *Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Dina Muin *Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Ilva Kristiana LangrateDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Stefan SchmitlDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Clemens P SpielvogelDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Barbara J FuegerDepartment of Biomedical Imaging and Image-Guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna, Vienna, 1090, Austria.
Xiang LiDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Gero KramerDepartment of Urology, Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Vienna, 1090, Austria.
Shahrokh F ShariatDepartment of Urology, Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Vienna, 1090, Austria.
Marcus HackerDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria. marcus.hacker@meduniwien.ac.at.ORCID 0000-0002-4222-4083
Sazan RasulDepartment of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile blocking androgen production and action effectively slows prostate cancer (PCa) progression, it is associated with significant side effects, including an increased risk of cardiovascular disease. Inflammatory activity within atherosclerotic arteries can be assessed using [

methodsThirty-two PCa patients receiving hormone therapy were compared to 17 age-matched PCa patients who had not undergone hormonal treatment in the 12 months prior to imaging. All participants underwent [

resultsPatients receiving hormone therapy exhibited significantly higher TBR

conclusionAdvanced PCa patients undergoing hormone therapy demonstrate increased arterial inflammation on [

Indexed as

Prostatic NeoplasmsAgedFluorodeoxyglucose F18HumansInflammationMaleMiddle AgedPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18[18F]FDGArterial inflammationAtherosclerosisHormone therapyPET/CTProstate cancer

Identifiers

PMID40526128
PMCPMC12660347

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.