Evidence map›Paper›PMID 40526127›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Predicting reverse remodeling following valve replacement in patients with valvular heart disease: a longitudinal

Ke Wang, Min Song, Hui Li, Yufan Gu, Kai Han, Chaowu Yan, Wei Fang, Lei Wang

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ke Wang *Department of Nuclear Medicine, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0002-1039-7385
Min Song *Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hui Li *Department of Ultrasound, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yufan GuDepartment of Nuclear Medicine, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Kai HanDepartment of Nuclear Medicine, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chaowu YanDepartment of Structural Heart Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0001-8864-5505
Wei FangDepartment of Nuclear Medicine, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lei WangDepartment of Nuclear Medicine, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. leiwangfw@126.com.ORCID 0000-0003-0273-6129

Funding

Beijing Nova Program 20230484328National High Level Hospital Clinical Research Funding 2024-GSP-TJ-2
6 · The paper itself

Abstract

purposeIn patients with valvular heart disease (VHD), fibroblast activation induced by pressure or volume overload can be identified by molecular imaging with fibroblast activation protein inhibitor (FAPI). The study sought to explore the potential of serial FAPI imaging for monitoring the reverse myocardial remodeling triggered by valve replacement.

methodsA cohort of 31 VHD patients scheduled for transcatheter or surgical valve replacement underwent

resultsMyocardial FAPI uptake showed heterogeneous among VHD patients (range: SUV

conclusion

Indexed as

Heart Valve DiseasesHeart Valve Prosthesis ImplantationMembrane ProteinsSingle Photon Emission Computed Tomography Computed TomographyVentricular RemodelingAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedMembrane ProteinsFibroblast activation proteinMolecular imagingReverse remodelingValvular heart disease

Identifiers

PMID40526127

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.