Evidence map›Paper›PMID 40526084›Full record

SynthesisAntimicrobial agents and chemotherapy2025

Antibiotic synergy against

Madeline Mellett, Alexander Lawandi, Chelsea Caya, Todd C Lee, Ahmed Babiker, Jesse Papenburg, Cedric P Yansouni, Matthew P Cheng

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. 1-Minute Pearls/Pitfalls for the Clinician.Journal of Brown hospital medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madeline MellettDepartment of Microbiology and Immunology, McGill University, Montreal, Québec, Canada.ORCID 0000-0002-1318-553X
Alexander LawandiDepartment of Critical Care Medicine, McGill University Health Centre, Montreal, Québec, USA.
Chelsea CayaResearch Institute of the McGill University Health Centre, Montreal, Québec, Canada.
Todd C LeeDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Québec, Canada.
Ahmed BabikerDivision of Infectious Diseases, Department of Medicine, Emory School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0003-0578-4871
Jesse PapenburgDivision of Pediatric Infectious Diseases, Department of Pediatrics, McGill University Health Centre, Montreal, Québec, Canada.ORCID 0000-0003-4232-871X
Cedric P YansouniDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Québec, Canada.ORCID 0000-0002-4765-3469
Matthew P ChengDivision of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal, Québec, Canada.ORCID 0000-0002-4867-2063

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Fonds de Recherche du Québec - SantéNational Institute of Allergy and Infectious Diseases UM1AI104681NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

Antimicrobial combinations have been extensively evaluated

Indexed as

Anti-Bacterial AgentsStaphylococcus aureusDrug SynergismHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsStaphylococcal InfectionsAnti-Bacterial Agentsantimicrobial combinationsStaphylococcus aureussynergy

Identifiers

PMID40526084
PMCPMC12326989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.