Evidence map›Paper›PMID 40526060›Full record

ArticleJournal of medicinal chemistry2025

Site-Selectively Functionalized Albumin with DFO*Maleimide for

Julia Kronberger, Theresa Balber, Hemma Schueffl, Raphaela Wahrmann, Anja Federa, Mathias Gradl, Marie R Brandt, Thomas Wanek, Markus Mitterhauser, Christian R Kowol and 2 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Improved Systemic Immunochemotherapy Employing an Oxaliplatin-TLR7/8 Agonist Prodrug Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julia KronbergerInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.ORCID 0009-0008-2432-097X
Theresa BalberLudwig Boltzmann Institute Applied Diagnostics, General Hospital of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria.
Hemma SchuefflCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, Vienna 1090, Austria.ORCID 0000-0002-9959-9716
Raphaela WahrmannCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, Vienna 1090, Austria.
Anja FederaInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.
Mathias GradlCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, Vienna 1090, Austria.
Marie R BrandtInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.
Thomas WanekDepartment of Biomedical Imaging and Image Guided Therapy, Preclinical Imaging Laboratory (PIL), Medical University of Vienna, Vienna 1090 Austria.
Markus MitterhauserInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.
Christian R KowolInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.ORCID 0000-0002-8311-1632
Thomas L MindtInstitute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria.ORCID 0000-0002-2090-1725
Petra HeffeterCenter for Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, Vienna 1090, Austria.ORCID 0000-0001-6401-8646

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human serum albumin (HSA) is a clinically validated drug carrier that improves drug delivery to tumor tissues. However, clinical imaging strategies are lacking to stratify patients who will benefit from HSA-bound drugs. In this study, we site-selectively radiolabeled HSA with zirconium-89 (

Indexed as

Colorectal NeoplasmsDeferoxaminePositron-Emission TomographyRadioisotopesRadiopharmaceuticalsSerum Albumin, HumanZirconiumAnimalsCell Line, TumorFemaleHumansMiceTissue DistributionDeferoxamineRadioisotopesRadiopharmaceuticalsSerum Albumin, HumanZirconiumZirconium-89

Identifiers

PMID40526060
PMCPMC12207588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.