Evidence map›Paper›PMID 40525824›Full record

ArticleeLife2025

Single-cell dissection of prognostic architecture and immunotherap response in

Xin Zhang, Guangyu Zhang, Shuli Sang, Yang Fei, Xiaopeng Cao, Wenge Song, Feide Liu, Jinze Che, Haoxia Tao, Hongwei Wang and 8 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xin Zhang *State Key Laboratory of Pathogen and Biosecurity, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, China.
Guangyu Zhang *Center for Immune Ageing and Rejuvenation, Department of Rheumatology and Immunology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Shuli Sang *State Key Laboratory of Pathogen and Biosecurity, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, China.
Yang Fei *Department of General Surgery, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Xiaopeng Cao *Department of Gastroenterology and Hepatology, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Wenge SongState Key Laboratory of Pathogen and Biosecurity, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, China.
Feide LiuDepartment of General Surgery, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Jinze CheDepartment of General Surgery, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Haoxia TaoState Key Laboratory of Pathogen and Biosecurity, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, China.
Hongwei WangDepartment of Pathology, Fourth Medical Center, Chinese PLA General Hospital, Beijing, China.
Lihua ZhangDepartment of Pathology, Fourth Medical Center, Chinese PLA General Hospital, Beijing, China.
Yiyan GuanState Key Laboratory of Pathogen and Biosecurity, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, China.
Shipeng RongDepartment of General Surgery, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Lijuan PeiDepartment of General Surgery, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Sheng YaoDepartment of General Surgery, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yanchun WangState Key Laboratory of Pathogen and Biosecurity, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-0203-7312
Min ZhangDepartment of Nephrology, First Medical Center of Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-7785-5475
Chunjie LiuState Key Laboratory of Pathogen and Biosecurity, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, China.

Funding

National Natural Science Foundation of China 82203636National Science and Technology Major Project Prevention and Treatment of Infectious Diseases (2018ZX10101003-005-005)Young Elite Scientist Sponsorship Program by CAST 2022QNRC001
6 · The paper itself

Abstract

Most of the human gastric cancer (GC) worldwide are ascribed to

Indexed as

Helicobacter InfectionsHelicobacter pyloriImmunotherapySingle-Cell AnalysisStomach NeoplasmsAgedFemaleGene Expression ProfilingHumansMaleMiddle AgedPrognosiscancer biologygastric cancerHelicobacter pylorihumanscRNA-seq

Identifiers

PMID40525824
PMCPMC12173458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.