Evidence map›Paper›PMID 40525629›Full record

ArticleJournal of veterinary internal medicine

Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019.

Oliver Waite, Ruth Gostelow, Emma Wright, Rosanne E Jepson, Dave C Brodbelt, Dan G O'Neill

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oliver WaiteDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hertfordshire, UK.ORCID https://orcid.org/0000-0002-4417-2547
Ruth GostelowDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hertfordshire, UK.ORCID https://orcid.org/0000-0001-9354-8291
Emma WrightDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hertfordshire, UK.
Rosanne E JepsonDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hertfordshire, UK.
Dave C BrodbeltPathobiology and Population Sciences, Royal Veterinary College, University of London, Hertfordshire, UK.
Dan G O'NeillPathobiology and Population Sciences, Royal Veterinary College, University of London, Hertfordshire, UK.ORCID https://orcid.org/0000-0003-1115-2723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus (DM) is a common endocrinopathy in cats. General population epidemiology and mortality studies on DM are lacking.

objectivesDescribe the incidence, prevalence, risk factors, and mortality for DM in cats under primary veterinary care in the United Kingdom (UK). ANIMALS: Random sample of 1053 confirmed DM cases from 1 255 130 cats in VetCompass.

methodsRetrospective cohort study with a nested case-control study. Period prevalence and incidence risk of DM for 2019 were calculated. Multivariable logistic regression modeling was used to identify risk factors for DM.

resultsAnnual prevalence was 0.39% (95% confidence interval [CI]: 0.37-0.42). Incidence risk (2019) was 0.14% (95% CI, 0.13-0.16). Mean age and median adult body weight of incident cases diagnosed with DM was 11.8 ± 3.5 years (n = 371) and 5.9 kg (interquartile range: 4.6-7.1, n = 327). Odds of DM were increased in cats ≥ 9.0 years (odds ratio [OR]: 5.11, CI, 4.10-6.24) compared with cats 4.5-9.0 years. Burmese (OR: 2.07, CI, 1.29-3.31) and Burmillas (OR: 8.30, CI, 2.59-26.62) had increased odds, whereas Bengals (OR: 0.24, CI: 0.06-0.98) and Ragdolls (OR: 0.11, CI: 0.02-0.80) had decreased odds of DM compared with crossbreeds. Of 51.2% (192/375) cats dead within 3 years of diagnosis, 93.0% (176/192) were euthanized; 19.7% (35/178) were euthanized ≤ 3 days after diagnosis. CONCLUSIONS AND CLINICAL IMPORTANCE: Almost 1/250 cats in the UK live with DM annually. Burmillas were predisposed to DM, and protection against DM was shown in Bengals and Ragdolls. Early mortality associated with DM diagnosis in cats is high.

Indexed as

Cat DiseasesDiabetes MellitusAnimalsCase-Control StudiesCatsFemaleIncidenceMalePrevalenceRetrospective StudiesRisk FactorsUnited Kingdombody weightdiabeticepidemiologyfirst opinion veterinary carepurebredVetCompass

Identifiers

PMID40525629
PMCPMC12171992

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.