Evidence map›Paper›PMID 40525460›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Perfusion imaging parameters predict long-term clinical outcome in isolated posterior cerebral artery occlusion stroke patients.

Hamza Adel Salim, Dhairya A Lakhani, Janet Me, Aneri Balar, Shenwen Huang, Meisam Hoseinyazdi, Licia Luna, Francis Deng, Nathan Z Hyson, Mona Bahouth and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Hamza Adel SalimDepartment of Neuroradiology, MD Anderson Medical Center, Houston, TX, USA.ORCID 0000-0002-5208-8425
Dhairya A LakhaniDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.ORCID 0000-0001-7577-1887
Janet MeDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Aneri BalarDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.ORCID 0000-0002-3592-708X
Shenwen HuangDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Meisam HoseinyazdiDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Licia LunaDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Francis DengDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Nathan Z HysonDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Mona BahouthDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Adam A DmytriwNeuroendovascular Program, Massachusetts General Hospital, Harvard University, Boston, MA, USA.ORCID 0000-0003-0131-5699
Adrien GuenegoDepartment of Diagnostic and Interventional Neuroradiology, Erasme University Hospital, Brussels, Belgium.ORCID 0000-0001-7281-1652
Gregory W AlbersDepartment of Interventional Neuroradiology, Stanford Medical Center, Palo Alto, CA, USA.
Hanzhang LuDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Victor C UrrutiaDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Kambiz NaelDepartment of Radiology & Biomedical Imaging, University of California, San Francisco, CA, USA.
Elisabeth B MarshDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Argye E HillisDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Rafael LlinasDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.
Max WintermarkDepartment of Neuroradiology, MD Anderson Medical Center, Houston, TX, USA.
Jeremy J HeitDepartment of Interventional Neuroradiology, Stanford Medical Center, Palo Alto, CA, USA.
Tobias D FaizyDepartment of Radiology, Neuroendovascular Program, University Medical Center Münster, Germany.
Vivek YedavalliDivision of Neuroradiology, Department of Radiology, Johns Hopkins Medical Center, Baltimore, MD, USA.ORCID 0000-0002-2450-4014

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sijin Wen · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

BackgroundIsolated posterior cerebral artery (PCA) occlusions, which account for 5% of ischemic strokes, significantly impact patient quality of life due to effects on the thalamus and visual cortex. Current guidelines for acute treatment and the prognostic utility of perfusion imaging in PCA strokes remain limited and underexplored.MethodsWe conducted a retrospective analysis of 21 patients with isolated PCA occlusions from January 2017 to March 2023 at two comprehensive medical institutions. Perfusion imaging parameters, including time-to-maximum (Tmax) > 4 s, Tmax > 6 s, Tmax > 8 s, Tmax > 10 s, and mismatch volume, were extracted. The primary outcome was the modified Rankin Scale (mRS) score at 90 days.ResultsThe median age of patients was 70 years, with 62% being male. Time-to-maximum > 4 s volume (rho = 0.46, 95% CI, 0.1-0.71,

Indexed as

CBVCT perfusionhypoperfusion intensity ratioIsolated posterior cerebral artery occlusionsMR perfusionperfusion imagingrCBFTmax

Identifiers

PMID40525460
PMCPMC12174088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.