Evidence map›Paper›PMID 40525182›Full record

ArticleAnnals of thoracic surgery short reports2025

Evaluating Novel Annuloplasty Ring Designs in a Pathophysiological Animal Model.

Sanchita S Bhat, Katelynne Berland, Beatrice E Ncho, Takayuki Kawashima, Satoshi Kozaki, Kaoru Uchida, Kazuki Mori, Robert C Gorman, Joseph H Gorman, Ajit P Yoganathan

Abstract read
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In one paragraph

Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sanchita S BhatWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia.
Katelynne BerlandWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia.
Beatrice E NchoWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia.
Takayuki KawashimaGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Satoshi KozakiGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Kaoru UchidaGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Kazuki MoriGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Robert C GormanGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Joseph H GormanGorman Cardiovascular Research Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Ajit P YoganathanWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Annuloplasty ring dehiscence post ischemic mitral regurgitation is an extensively studied mode of failure. This study aimed to compare annuloplasty ring designs of varying stiffness and investigate annular forces to understand mechanisms that may mitigate likelihood of ring dehiscence. Methods: Force transducers were attached to 5 types of rings-rigid, flexible, COM-Flex, POST-Flex, and ALPM-Flex-having varying stiffness. After undersized ring implantation in diseased animals (N = 31), ring suture forces (F Results: In normotensive animals, anterior F Conclusions: Results demonstrate trends in suture forces and their spatial variation. COM-Flex was most effective in distributing forces away from posterior annulus. Despite POST-Flex having large material heterogeneity, average posterior force was similar to rigid rings. Results shown in this study provide an atlas of data on how variable annular loading is and the complexity of both understanding loads and developing devices to sustain them.

Identifiers

PMID40525182
PMCPMC12167570

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.