ArticleAnnals of thoracic surgery short reports2025
Outcomes with Sublobar Resection vs Lobectomy in Patients With cT1N0M0 Large-cell Neuroendocrine Cancer.
Article in Annals of thoracic surgery short reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Large-cell neuroendocrine cancer (LCNEC) is a rare tumor histology associated with poor prognosis. This study aimed to analyze outcomes with sublobar resection in patients with clinical T1N0M0 LCNEC (<3 cm) compared with lobectomy. Methods: We performed a single-institution, retrospective study comparing patients undergoing lobectomy vs sublobar resection (segmentectomy or wedge resection) for clinical T1N0M0 LCNEC from 2002 2022. We performed unmatched and propensity-matched comparisons for overall survival and recurrence-free survival. Results: During the study period, 62 lobectomies and 34 sublobar resections (20 segmentectomies and 14 wedge resections) were performed for clinical T1N0M0 LCNEC. Correct pre-/intraoperative histologic diagnosis was made only for 21 patients receiving lobectomy (33.9%) and 10 patients receiving sublobar resection (29.4%). In the unmatched cohort, there was no difference in overall survival (median, 65.6 vs 65.4 months; Conclusions: LCNEC is a diagnostic challenge with pre-/intra-operative biopsy. For cT1N0M0 LCNEC, even though the survival was not inferior, sublobar resection could be inferior in long-term locoregional disease control. An individualized approach is warranted in case LCNEC is diagnosed after sublobar resection.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.