ArticleJournal of surgical case reports2025
Unlabeled topical anesthetic-induced severe methemoglobinemia in a pediatric burn patient.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
This case report presents a patient with acquired methemoglobinemia due to unlabeled local anesthetic use. Some local anesthetics disrupt oxidative phosphorylation in erythrocytes, forming methemoglobin, which cannot transport oxygen. A 10-year-old boy with 60% total body surface area flame burns experienced sudden deterioration on Day 6 in the pediatric intensive care unit, presenting with cyanosis, tachycardia, hypotension, and SpO2 of 76% on room air, improving to 90% on 100% FiO2. A telemedicine consultation was requested, and evaluation revealed an elevated methemoglobin level of 22%. The source was an inadequately labeled ointment containing prilocaine used for burn wound care. This case underscores the importance of vigilant monitoring when using local anesthetics on pediatric burn patients. Additionally, global telemedicine played a crucial role in the timely diagnosis and management of this rare but life-threatening condition.
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