Evidence map›Paper›PMID 40525051›Full record

ReviewCureus2025

The Role of Sleep and the Effects of Sleep Loss on Cognitive, Affective, and Behavioral Processes.

Anna Hyndych, Rima El-Abassi, Edward C Mader

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Trial
  2. Heat-TreatedNutrients · 2025
    Trial
  3. Review
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  5. Article
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  9. Review
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  14. Review
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  18. Clinical significance of ADHD traits in central disorders of hypersomnolence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna HyndychSleep and Health Research Program, University of Arizona College of Medicine - Tucson, Tucson, USA.
Rima El-AbassiDepartment of Neurology, Louisiana State University Health Sciences Center, New Orleans, USA.
Edward C MaderDepartment of Neurology, Louisiana State University Health Sciences Center, New Orleans, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep is essential for various cognitive, affective, and behavioral processes, including attention, memory, executive function, emotional regulation, and interpersonal interactions. Sleep disruptions undermine these functions, resulting in measurable impairments in daily activities, occupational performance, and public safety. Adequate sleep supports sustained vigilance and concentration, whereas sleep deprivation is associated with attentional lapses, diminished cognitive control, and impaired sensory processing. Memory consolidation, which depends on both non-rapid eye movement (NREM) and rapid eye movement (REM) sleep, is particularly susceptible to disruption by sleep loss. Executive functions, such as working memory, impulse control, and decision-making, are notably impaired due to the prefrontal cortex's heightened sensitivity to insufficient sleep. Sleep deprivation increases amygdala reactivity, weakens prefrontal-amygdala connectivity, and contributes to emotional dysregulation, impulsivity, and risk-taking behaviors. Chronic sleep deprivation exacerbates cognitive deficits, emotional instability, and motor performance decline, leading to higher error rates and reduced workplace productivity. Given its widespread consequences, chronic sleep deprivation constitutes a significant public health concern. This narrative review synthesizes contemporary research on the effects of sleep and sleep loss on waking behavior, with a focus on attention, memory, executive function, emotional regulation, and daytime performance.

Indexed as

attentionbehaviorcognitiondaytime performanceemotionexecutive functionmemorysleepsleep deprivationsocial

Identifiers

PMID40525051
PMCPMC12168795

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.