Evidence map›Paper›PMID 40525017›Full record

ArticleCureus2025

Refractory Disseminated Intravascular Coagulation Caused by Endovascular Invasion of Squamous Cell Carcinoma of the Lung: A Case Report.

Yutaka Tsukamoto, Masataka Umeda, Takashi Sugimoto, Yuki Matsuoka, Takeharu Kato, Masahiro Nakashima, Koya Ariyoshi, Takahiro Maeda

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yutaka TsukamotoDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, JPN.
Masataka UmedaDepartment of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN.
Takashi SugimotoDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, JPN.
Yuki MatsuokaDepartment of Pathology, Nagasaki University Hospital, Nagasaki, JPN.
Takeharu KatoDepartment of Hematology, Nagasaki University Hospital, Nagasaki, JPN.
Masahiro NakashimaDepartment of Pathology, Nagasaki University Hospital, Nagasaki, JPN.
Koya AriyoshiDepartment of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, JPN.
Takahiro MaedaDepartment of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated intravascular coagulation (DIC) is a systemic intravascular activation of coagulation caused by various underlying conditions. Severe DIC cases could be fatal. We present a 78-year-old Japanese man who developed uncontrollable DIC, finally diagnosed as lung cancer and intravascular invasion along the endothelium of the pulmonary artery, massive pulmonary embolism, and tumor embolism in autopsy. Leucocytes, platelets, and cancer cells play roles in uncontrollable DIC by assisting the attachment of cancer cells to endothelia. Endothelium damage enhances coagulation and suppresses fibrinolysis. This is the first case of uncontrollable DIC caused by intravascular invasion of lung cancer along the endothelium.

Indexed as

disseminated intravascular coagulationendothelium damageendovascular invasionlung cancersquamous cell carcinoma

Identifiers

PMID40525017
PMCPMC12168749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.