ReviewCureus2025
Risk Factors and Cumulative Incidence of Cystoid Macular Edema After Simple Cataract Surgery: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Visual outcome, safety, and complications of iris suture fixation versus iris claw fixation for aphakic correction: a prospective randomized study.BMC ophthalmology · 2026Trial
- Comparison of topical nepafenac 0.1% and 0.3% for the treatment of pseudophakic cystoid macular edema following cataract surgery.BMC ophthalmology · 2026Article
- Comparative outcomes of posterior sub-Tenon triamcinolone for pseudophakic cystoid macular edema in diabetic and non-diabetic patients: a retrospective study.BMC ophthalmology · 2026Article
- Article
- Irvine-Gass Syndrome Personalized Treatment Outcomes: A Retrospective Single-Center Cohort Study.Journal of personalized medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pseudophakic cystoid macular edema (PCME) is a common side effect following cataract surgery, especially in patients with systemic and/or ocular comorbidities. Research evidence has established the impact of cataract surgery on PCME occurrence; various risk factors could contribute to PCME development, as indicated by epidemiological studies. This research aims to examine the cumulative incidence of PCME and explore the correlation between PCME occurrence, ophthalmic, systemic, and surgery-related risk factors after uncomplicated cataract surgery. PubMed and EMBASE databases were used for this systematic search (end-date of search: March 31, 2024). Random-effects (DerSimonian-Laird) models were used to estimate the pooled cumulative incidence, pooled relative risk (RR), and 95% confidence intervals (95% CIs). Subgroup analyses, sensitivity analyses, and meta-regression analyses were also carried out. The meta-analysis concerning cumulative PCME incidence included 143 studies. Thirty-seven studies were included in a meta-analysis of possible PCME risk factors. Pooled cumulative PCME incidence was found to be 5%. PCME was more frequent in patients with diabetes mellitus (DM) (RR=2.87, 95%Cl: 1.96-4.21), epiretinal membrane (ERM) (RR=4.51, 95%Cl: 3.06-6.64), uveitis (RR=6.76, 95%Cl: 2.49-18.31), pars plana vitrectomy (PPV) (RR=4.11, 95%Cl: 1.86-9.11) and retinal vein occlusion (RVO) (RR=8.79, 95%Cl: 1.90-40.76). DM, ERM, uveitis, PPV, and RVO were associated with PCME. Additional prospective cohort studies investigating various risk factors seem desirable.
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