Evidence map›Paper›PMID 40524987›Full record

ArticleCureus2025

Neurotoxic Myelitis Following Accidental Epidural Injection of Chlorhexidine During Obstetric Epidural Anesthesia: A Case Report.

Badie Douqchi, Omar Alaoui Mhammedi, Doaae El Ouaddane, Amine Elmouhib, Mohammed El Aissaouy, Houssam Bkiyar, Brahim Housni

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Badie DouqchiDepartment of Anesthesia and Reanimation, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Omar Alaoui MhammediDepartment of Anesthesia and Reanimation, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Doaae El OuaddaneDepartment of Anesthesia and Reanimation, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Amine ElmouhibDepartment of Anesthesia and Reanimation, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Mohammed El AissaouyDepartment of Anesthesia and Reanimation, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Houssam BkiyarDepartment of Anesthesia and Reanimation, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Brahim HousniDepartment of Anesthesia and Reanimation, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of neurotoxic myelitis following the accidental epidural injection of chlorhexidine during obstetric anesthesia at a peripheral hospital. A 32-year-old parturient in labor received an epidural catheter for vaginal delivery, during which 3 mL of chlorhexidine was mistakenly injected into the epidural space. This led to progressive paraplegia, severe headaches, and respiratory distress requiring intubation. The patient was subsequently transferred to our anesthesia and critical care department for further management. Radiological findings revealed centromedullary edema and myelitis. Her condition improved with steroid therapy to reduce the inflammatory response, along with strict monitoring. Paraplegia nearly resolved within 72 hours, with complete functional recovery one week later. This study highlights the serious risks of accidental intrathecal drug administration and underscores the need for heightened vigilance and safety measures in anesthesia practice.

Indexed as

anesthesiacase reportchlorhexidine myelitisintrathecal injectionneurotoxic myelitis

Identifiers

PMID40524987
PMCPMC12169915

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.