ArticleCureus2025
Primary Cardiac Diffuse Large B-Cell Lymphoma Managed With Rituximab, Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (R-EPOCH): A Case Report and Literature Review.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Primary Cardiac Diffuse Large B-Cell Lymphoma: A Diagnostic Pitfall With Overlapping Imaging Features.JACC. Case reports · 2026Article
- Rapid symptomatic and metabolic response to emergency radiotherapy in a critically ill patient with primary cardiac lymphoma: a multidisciplinary case report.Cardio-oncology (London, England) · 2026Article
- Large B-Cell Lymphoma Invading the Heart: Insights From Multimodality Imaging in a Young Woman.JACC. Case reports · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma. However, primary cardiac involvement is rare, often presenting with subtle and atypical symptoms that complicate diagnosis and management. We present the case of a 60-year-old man who presented with intermittent palpitations of unclear origin, later identified as ventricular tachycardia. Imaging showed a right ventricular cardiac mass, and biopsy confirmed a diagnosis of DLBCL. He was treated with the chemotherapy regimen rituximab, etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (R-EPOCH), resulting in symptomatic resolution of palpitations and a reduction in the size of the cardiac mass. Early detection is crucial to improving survival in primary cardiac lymphomas and highlights the importance of an interdisciplinary approach in managing this rare cardiac malignancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.