Evidence map›Paper›PMID 40524872›Full record

ArticleJournal of hepatocellular carcinoma2025

Intravoxel Incoherent Motion Improves the Accuracy of Preoperative Prediction of Vessels Encapsulating Tumor Clusters in Hepatocellular Carcinoma.

Min Li, Ge Zhang, Jing Li, Yufan Ren, Xuan Jin, Qiying Ke, Congyue Guo, Jiaqi Lv, Haojun Lu, Yongzhou Xu and 3 more

Abstract read
In one paragraph

Article in Journal of hepatocellular carcinoma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Min Li *Department of Radiology, Chengdu Sixth People's Hospital, Chengdu, Sichuan, People's Republic of China.
Ge Zhang *Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Jing Li *Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Yufan RenDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Xuan JinDepartment of Radiology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, Zhejiang, People's Republic of China.
Qiying KeDepartment of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.
Congyue GuoDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Jiaqi LvDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Haojun LuDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Yongzhou XuPhilips Healthcare, Guangzhou, People's Republic of China.
Wen LiangDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Xianyue QuanDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.ORCID 0000-0003-2293-9345
Xinming LiDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Hepatocellular carcinoma (HCC) with vessels encapsulating tumor clusters (VETC) pattern presents a higher risk of recurrence and metastasis, and the unique vascular structure of the VETC pattern may affect the perfusion and diffusion, and the effect that can be captured by intravoxel incoherent motion (IVIM). Therefore, this study used preoperative IVIM to predict VETC pattern in HCC and performed preoperative noninvasive recurrence risk stratification. Patients and Methods: Patients with suspicious HCC were included prospectively. Two radiologists independently evaluated radiologic features and measured apparent diffusion coefficient (ADC), true diffusion coefficient ( Results: The consecutive cohort included 116 patients (mean age, 55 years ± 11, 94 men). Twenty-nine of the 116 HCC (25.0%) were VETC HCC. The Conclusion: IVIM enhances the accuracy of preoperative prediction of the VETC pattern and provides preoperative noninvasive risk stratification for HCC recurrence.

Indexed as

diffusion-weighted imaginghepatocellular carcinomaintravoxel incoherent motionrecurrence-free survivalvessels encapsulating tumor clusters

Identifiers

PMID40524872
PMCPMC12168965

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.