Evidence map›Paper›PMID 40524735›Full record

ArticleFood hydrocolloids for health2025

Optimization of phenolic extraction method and

Rhowell Navarro Tiozon, Glenn Vincent P Ong, Kristel June D Sartagoda, Sheba Mae M Duque, Saleh Alseekh, Aldrin P Bonto, Shem Gempesaw, Vipin Pratap, Florencio C Reginio, Jonina Marie J Tengco and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food hydrocolloids for health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rhowell Navarro TiozonConsumer-driven Grain Quality and Nutrition Center, Rice Breeding Innovations Platform, International Rice Research Institute, Los Baños 4030, Philippines.
Glenn Vincent P OngConsumer-driven Grain Quality and Nutrition Center, Rice Breeding Innovations Platform, International Rice Research Institute, Los Baños 4030, Philippines.
Kristel June D SartagodaConsumer-driven Grain Quality and Nutrition Center, Rice Breeding Innovations Platform, International Rice Research Institute, Los Baños 4030, Philippines.
Sheba Mae M DuqueInstitute of Food Science and Technology, College of Agriculture and Food Science, University of the Philippines Los Baños College, Laguna 4031, Philippines.
Saleh AlseekhMax-Planck-Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam-Golm, 14476, Germany.
Aldrin P BontoDepartment of Chemistry, College of Science, De La Salle University, 2401 Taft, Avenue, Manila 0922, Philippines.
Shem GempesawDepartment of Food Science and Chemistry, University of the Philippines Mindanao, Mintal, Tugbok District, Davao City 8000, Philippines.
Vipin PratapCentre of Excellence in Rice Value Addition (CERVA), (IRRI)-South Asia Regional Centre (ISARC), International Rice Research Institute, Varanasi, Uttar Pradesh, India.
Florencio C ReginioInstitute of Food Science and Technology, College of Agriculture and Food Science, University of the Philippines Los Baños College, Laguna 4031, Philippines.
Jonina Marie J TengcoInstitute of Food Science and Technology, College of Agriculture and Food Science, University of the Philippines Los Baños College, Laguna 4031, Philippines.
Christian SeaganDepartment of Chemistry, College of Science, De La Salle University, 2401 Taft, Avenue, Manila 0922, Philippines.
Joel H G TolentinoDepartment of Food Science and Chemistry, University of the Philippines Mindanao, Mintal, Tugbok District, Davao City 8000, Philippines.
Dennis Marvin O SantiagoInstitute of Food Science and Technology, College of Agriculture and Food Science, University of the Philippines Los Baños College, Laguna 4031, Philippines.
Alisdair R FernieMax-Planck-Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam-Golm, 14476, Germany.
Nese SreenivasuluConsumer-driven Grain Quality and Nutrition Center, Rice Breeding Innovations Platform, International Rice Research Institute, Los Baños 4030, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pigmented paddy rice is rich in a diverse array of phytochemicals that confer notable antioxidant and anticancer properties. However, the stability and bioaccessibility of these bioactive compounds present significant challenges. In this study, 542 brown (including pigmented and non-pigmented) whole grain rice samples were screened for their antioxidant components and capacity, leading to the identification of three superior cultivars: Balatinao variable purple rice, Ketan Hitam variable purple rice, and Kintuman red rice. Using response surface methodology, rice bran extracts from these cultivars were subjected to microencapsulation to stabilize the phytochemicals. Among the microencapsulated rice bran extracts (MRBEs), Ketan Hitam MRBE demonstrated significantly higher total phenolic content (TPC) and antioxidant capacity. This enhancement is likely due to the increased concentrations of isovitexin, luteolin 7-glucoside, and vitexin following microencapsulation. Furthermore, compared to non-encapsulated rice bran extracts, MRBEs exhibited significantly improved anticancer activity against HCT116 (colon) and A549 (lung) cancer cell lines (

Indexed as

AnticancerAntioxidantBioaccessibilityMicroencapsulationPhenolicsPigmented rice

Identifiers

PMID40524735
PMCPMC12167174

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.