Evidence map›Paper›PMID 40524733›Full record

ReviewCurrent treatment options in psychiatry2025

Artificial Intelligence in Obsessive-Compulsive Disorder: A Systematic Review.

Jiyeong Kim, Juan Pablo Gonzalez Pacheco, Ashleigh Golden, Elias Aboujaoude, Peter van Roessel, Aayushi Gandhi, Pavithra Mukunda, Tatevik Avanesyan, Haopeng Xue, Ehsan Adeli and 7 more

Abstract readReview
In one paragraph

Review in Current treatment options in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jiyeong KimStanford Center for Digital Health, Stanford School of Medicine, Stanford, CA USA.
Juan Pablo Gonzalez PachecoDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Ashleigh GoldenDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Elias AboujaoudeDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Peter van RoesselDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Aayushi GandhiDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Pavithra MukundaDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Tatevik AvanesyanDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Haopeng XueDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Ehsan AdeliDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Jane Paik KimDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Manish SaggarDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Shannon Wiltsey StirmanDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Eric KuhnDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Kaustubh SupekarDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Kilian M PohlDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.
Carolyn I RodriguezDepartment of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford, CA USA.

Funding

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCDR01MH133553 · NIMH · STANFORD UNIVERSITY · PI Carolyn I Rodriguez · 2023 to 2026
$2.9M
Identifying, Validating, and Characterizing Biological Subtypes of PsychiatricDisorders Using a Novel Computational FrameworkR01LM014597 · NLM · STANFORD UNIVERSITY · PI Kaustubh Satyendra Supekar · 2024 to 2026
$1.0M
Leveraging Large Language Models and Machine Learning Algorithms to Assess Depression and Anxiety Symptoms and Risks for Patients with Cardiovascular Disease or Diabetes MellitusK01MH137386 · NIMH · STANFORD UNIVERSITY · PI Jiyeong Kim · 2024 to 2026
$406k
NIMH NIH HHS K01 MH137386NIMH NIH HHS R01 MH133553NLM NIH HHS R01 LM014597
6 · The paper itself

Abstract

Purpose of Review: Obsessive-compulsive disorder (OCD) is a chronic and disabling condition, often leading to significant functional impairments. Despite its early onset, there is an average delay of 17 years from symptom onset to diagnosis and treatment, resulting in poorer outcomes. This systematic review aims to synthesize current findings on the application of AI in OCD, highlighting opportunities for early symptom detection, scalable therapy training, clinical decision support, novel therapeutics, computer vision-based approaches, and multimodal biomarker discovery. Recent Findings: While previous reviews focused on biomarker-based OCD detection and treatment using machine learning (ML), the findings of the current review add information about novel applications of deep learning technology, specifically generative artificial intelligence (GenAI) and natural language processing (NLP). Among the included 13 articles, most studies (84.6%) utilized secondary data analyses, primarily through GenAI/NLP. Nearly 77% of these studies were published in the past two years, with high quality of evidence. The primary focus areas were enhancing treatment and management, and timely OCD detection (both 38.5%); followed by AI tool development for broader mental health applications. Summary: AI technologies offer transformative potential for improvements related to OCD if diagnosis occurs earlier after onset; thereby lessening the consequential economic burden. Prioritizing investment in ethically sound AI research could significantly improve OCD outcomes in mental health care. Supplementary Information: The online version contains supplementary material available at 10.1007/s40501-025-00359-8.

Indexed as

AIDiagnosisMental healthObsessive-compulsive disorderOCDTreatment

Identifiers

PMID40524733
PMCPMC12167270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.