Evidence map›Paper›PMID 40524494›Full record

ArticleeLife2025

Executioner caspase is proximal to Fasciclin 3 which facilitates non-lethal activation in

Masaya Muramoto, Nozomi Hanawa, Misako Okumura, Takahiro Chihara, Masayuki Miura, Natsuki Shinoda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masaya Muramoto *Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Nozomi Hanawa *Department of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0001-3852-7508
Misako OkumuraProgram of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.ORCID https://orcid.org/0000-0003-3162-0416
Takahiro ChiharaProgram of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.ORCID https://orcid.org/0000-0001-9989-3619
Masayuki MiuraDepartment of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7444-5705
Natsuki ShinodaDepartment of Genetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6668-8747

Funding

Japan Agency for Medical Research and Development JP21gm5010001Ministry of Education, Culture, Sports, Science and Technology 19K16137Ministry of Education, Culture, Sports, Science and Technology 21H04774Ministry of Education, Culture, Sports, Science and Technology 21K15080Ministry of Education, Culture, Sports, Science and Technology 22H05586Ministry of Education, Culture, Sports, Science and Technology 23H04766Ministry of Education, Culture, Sports, Science and Technology 23K05747Ministry of Education, Culture, Sports, Science and Technology 24H00567Ministry of Education, Culture, Sports, Science and Technology 25H01842
6 · The paper itself

Abstract

The nervous system undergoes functional modification independent of cell turnover. Caspase participates in reversible neuronal modulation via non-lethal activation. However, the mechanism that enables non-lethal activation remains unclear. Here, we analyzed proximal proteins of

Indexed as

CaspasesCell Adhesion Molecules, NeuronalDrosophila melanogasterDrosophila ProteinsOlfactory Receptor NeuronsAnimalsCaspasesCell Adhesion Molecules, NeuronaldrICE protein, Drosophiladronc protein, DrosophilaDrosophila Proteinscaspasecaspase-dependent non-lethal cellular processescell biologyD. melanogasterMASCaTneuroscienceolfactionTurboID

Identifiers

PMID40524494
PMCPMC12173457

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.