Evidence map›Paper›PMID 40524196›Full record

Trial reportChiropractic & manual therapies2025

Dry cupping therapy combined with conventional therapy does not provide additional benefits over conventional therapy alone in patients with non-specific chronic low back pain: a randomized trial.

Renjie Xu, Yun Yang, Chengjie Yan, Zhou Li, Chaochen Zhao, Jingming Ma, Guangxu Xu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Chiropractic & manual therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Renjie XuRehabilitation Treatment Department, Kunshan Rehabilitation Hospital, Kunshan, Jiangsu, China.
Yun Yang *Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Gulou District, Nanjing City, Jiangsu, China.
Chengjie YanDepartment of Neurological Rehabilitation, Kunshan Rehabilitation Hospital, Kunshan, Jiangsu, China.
Zhou LiRehabilitation Treatment Department, Kunshan Rehabilitation Hospital, Kunshan, Jiangsu, China.
Chaochen ZhaoRehabilitation Treatment Department, Kunshan Rehabilitation Hospital, Kunshan, Jiangsu, China.
Jingming MaRehabilitation Treatment Department, Kunshan Rehabilitation Hospital, Kunshan, Jiangsu, China.
Guangxu Xu *School of Rehabilitation Medicine, Nanjing Medical University, Nanjing, Jiangsu, China. xuguangxu1@126.com.

Funding

Science and Technology Bureau of Kunshan KS2252
6 · The paper itself

Abstract

purposeChronic non-specific low back pain (CNLBP) is a complex and heterogeneous condition, and it is necessary to explore new treatment approaches. We evaluated whether the addition of dry cupping therapy to guideline‑based conventional therapy would further improve clinical outcomes in CNLBP.

methodsThirty-six patients with CNLBP were recruitedand randomly divided into two groups: the control group and the intervention group. The intervention group received cupping therapy in addition to the control group (core stabilization exercises, spinal manipulation and education) for 4 weeks. The primary outcome was the visual analog scale (VAS) for pain intensity. Secondary outcomes were the Roland Morris disability questionnaire (RMDQ), and pressure pain thresholds (PPT) at bilateral Shenshu (BL23), Qihaishu (BL24), and Dachangshu (BL25) acupuncture points.

resultsAt week 4 the between‑group difference in resting pain was trivial (median difference 0.0 cm, 95% CI - 1.0 to 1.0). Neither clinically important nor statistically significant differences were detected in disability or PPTs. Both groups improved substantially from baseline.

conclusionIn this randomized trial, adding dry cupping to conventional therapy offered no additional benefit over conventional therapy alone for pain, disability or PPT in CNLBP. Larger, multicentre trials with longer follow‑up and standardized negative pressures are warranted.

trial registrationChiCTR2300069398, http://www.chictr.org.cn , Registration Date: March 15, 2023.

Indexed as

Chronic PainCupping TherapyLow Back PainAdultCombined Modality TherapyFemaleHumansMaleMiddle AgedPain MeasurementPain ThresholdTreatment OutcomeChronic non-specific low back painCuppingDisabilityPainPain pressure threshold

Identifiers

PMID40524196
PMCPMC12168300

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.