Evidence map›Paper›PMID 40524112›Full record

Trial reportAIDS and behavior2025

A Randomized Comparison Trial Testing Two Culturally Adapted HIV Prevention Approaches for Native Americans Reducing Trauma Symptoms Versus Substance Misuse.

C R Pearson, D Huh, M Bedard-Gilligan, D Walker, R A Marín, K Saluskin, D Kaysen

Erratum issuedAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

C R PearsonIndigenous Wellness Research Institute, School of Social Work, University of Washington, Box 354900, Seattle, WA, 98105-6299, USA. pearsonc@uw.edu.ORCID https://orcid.org/0000-0003-4711-215X
D HuhIndigenous Wellness Research Institute, School of Social Work, University of Washington, Box 354900, Seattle, WA, 98105-6299, USA.
M Bedard-GilliganDepartment of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA, USA.
D WalkerInnovative Programs Research Group, School of Social Work, University of Washington, Seattle, WA, USA.
R A MarínIndigenous Wellness Research Institute, School of Social Work, University of Washington, Box 354900, Seattle, WA, 98105-6299, USA.
K SaluskinYakama Nation Department of Health, Toppenish, WA, USA.
D KaysenDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Scientific/Technical CoreP2CHD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI SARA R. CURRAN · 2017 to 2026
$6.3M
Preventing HIV among Native Americans through the treatment PTSD & substance useR01MD011574 · NIMHD · UNIVERSITY OF WASHINGTON · PI KAYSEN, DEBRA L, PEARSON, CYNTHIA RENEE · 2016 to 2020
$3.3M
Innovative Computational Tools and Best Practice Recommendations for Analyzing HIV-related Count OutcomesR21AI179404 · NIAID · UNIVERSITY OF WASHINGTON · PI HUH, DAVID · 2024 to 2025
$435k
NCATS NIH HHS UL1 TR002319NIAID NIH HHS R21 AI179404NICHD NIH HHS P2C HD042828NIMHD NIH HHS MD1MD011574NIMHD NIH HHS R01 MD011574
6 · The paper itself

Abstract

We compared two counseling approaches aimed at preventing HIV: Narrative Exposure Therapy (NET) targeting posttraumatic stress disorder (PTSD) and Motivational Interviewing with CBT-skills training (MIST), addressing substance misuse. We recruited 125 participants aged 16 + rural American Indians. Participants were screened for current sexual activity, probable PTSD, and substance misuse, then randomly assigned to either NET or MIST. Interventions were culturally adapted and up to 6 sessions delivered by local counselors. Primary outcomes included PTSD severity, number of sexual partners, frequency of sex, sex while using substances, and overall substance use. Both treatments reduced PTSD severity, risky sexual behavior, number of sexual partners, sexual encounters with unknown HIV serostatus partners, and substance use symptoms at follow-up. However, NET showed greater effectiveness than MIST, specifically in reducing risky sexual behaviors and substance use. Results suggest that interventions addressing either PTSD symptoms or substance misuse can effectively reduce HIV sexual risk behaviors.

Indexed as

Cognitive Behavioral TherapyHIV InfectionsIndians, North AmericanMotivational InterviewingStress Disorders, Post-TraumaticSubstance-Related DisordersAdolescentAdultCounselingFemaleHumansMaleMiddle AgedRisk-TakingSexual BehaviorSexual Partners

Identifiers

PMID40524112
PMCPMC12732329

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.