Evidence map›Paper›PMID 40523998›Full record

SynthesisLasers in medical science2025

Photobiomodulation treatment in incomplete spinal cord injuries or peripheral nerve injuries: a comprehensive systematic review of randomized clinical trials.

Gustavo Henrique Weimer, Cláudio Felipe Kolling da Rocha

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gustavo Henrique WeimerFeevale University, Novo Hamburgo, Brazil. gustavohweimer@gmail.com.
Cláudio Felipe Kolling da RochaFeevale University, Novo Hamburgo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this systematic review was to identify if photobiomodulation therapy improves motor and/or sensory outcomes in patients with incomplete spinal cord injuries (SCI) or peripheral nerve injuries (PNI). Searches in Pubmed, Embase, Scopus and Web of Science databases were conducted with publication date limit from 01/01/2012 to 05/01/2024. Inclusion criteria: randomized clinical trials evaluating photobiomodulation therapy in incomplete spinal cord injuries or peripheral nerve injuries; wavelengths between 620 nm and 1400 nm. Exclusion criteria: lack of control or comparator group; studies in patients with complete SCI or other pathologies as diabetic or chemotherapy-induced neuropathies, rheumatic diseases, fibromyalgia, complex regional pain syndrome; studies on cranial nerves were excluded. nineteen studies were included in this review: fourteen studies assessed effects of PBM in carpal tunnel syndrome, one in ulnar nerve compression, one in brachial plexus injury, one in lumbar radiculopathy and two articles in incomplete spinal cord injuries. There is great heterogeneity of reported device configuration and irradiation parameters that made data synthesis difficult. Despite small samples and duration of follow up, there is evidence of an inclination toward improvement in strength, sensitivity, and pain in patients undergoing PBM therapy for SCI and PNI.

Indexed as

Low-Level Light TherapyPeripheral Nerve InjuriesSpinal Cord InjuriesHumansRandomized Controlled Trials as Topic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.