ArticleCommunications chemistry2025
Phosphorylation of nucleosides by P-N bond species generated from prebiotic reduced phosphorus sources.
Article in Communications chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Concurrent Phosphite Oxidation and Adenosine Phosphorylation Under Prebiotic Evaporative Conditions.Journal of molecular evolution · 2026Article
- Non-equilibrium preparation of (Chemical science · 2026Article
- Ortho-phosphiteACS central science · 2026Article
- Various inorganic phosphorus species in prebiotic Earth and extraterrestrial settings.Discover chemistry · 2026Review
- A scope of prebiotic neat reaction conditions and the mechanism of urea-assisted phosphorylations of alcohols.Nature communications · 2025Article
- Thermal Decomposition and Prebiotic Formation of Adenosine Phosphates in Simulated Early-Earth Evaporative Settings.Molecules (Basel, Switzerland) · 2025Article
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Authors and funding
4 authors.
Funding
Abstract
P-N species e.g., amidophosphates readily phosphorylate organics, thereby overcoming the so-called 'Phosphate Problem'. However, the formation of amidophosphates by plausible early Earth geochemical pathways is limited. We herein show that ammonolysis of the prebiotically plausible dimer of phosphite, pyrophosphite, readily affords amidophosphite, the monomeric P-N derivative of phosphite. Amidophosphite then undergoes spontaneous oxidation to form monoamidophosphate (MAP) and diamidophosphate (DAP) at room temperature (yields of the inorganic P-N species up to 48%). Oxidation of amidophosphite is promoted by O
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