Evidence map›Paper›PMID 40523847›Full record

ArticleJournal of medicinal chemistry2025

Exploring Linear

Weihong Liu, Luca S Dobson, Chen Zhang, Jiahui Sun, Phillip T Lowe, Yingjian Liu, Hanyi Zhuang, David O'Hagan

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Microbial volatile organic compounds and olfactory receptors in wound malodor.Frontiers in cellular and infection microbiology · 2026
    Pooled it
  2. Article
  3. Article
  4. A newly-processed Meicha (Food chemistry: X · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Weihong LiuIntelligent Perception Lab, Hanwang Technology Co., Ltd, Beijing 100193, China.
Luca S DobsonSchool of Chemistry, University of St Andrews, North Haught, St Andrews KY16 9ST, U.K.
Chen ZhangIntelligent Perception Lab, Hanwang Technology Co., Ltd, Beijing 100193, China.
Jiahui SunIntelligent Perception Lab, Hanwang Technology Co., Ltd, Beijing 100193, China.
Phillip T LoweSchool of Chemistry, University of St Andrews, North Haught, St Andrews KY16 9ST, U.K.
Yingjian LiuIntelligent Perception Lab, Hanwang Technology Co., Ltd, Beijing 100193, China.
Hanyi ZhuangIntelligent Perception Lab, Hanwang Technology Co., Ltd, Beijing 100193, China.
David O'HaganSchool of Chemistry, University of St Andrews, North Haught, St Andrews KY16 9ST, U.K.ORCID 0000-0002-0510-5552

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structure-activity relationship studies on olfactory receptors such as OR1A1 enhance an understanding of the molecular mechanism of olfactory perception. Such receptors are considered to be important in regulating physiological roles beyond olfactory perception. Here a series of linearized ketones, alcohols, and a cyclic ether, extended between the oxygen functionality and a terminal

Indexed as

AcetyleneReceptors, OdorantAcetophenonesHumansLigandsMolecular Docking SimulationMolecular Dynamics SimulationStereoisomerismStructure-Activity RelationshipAcetophenonesAcetyleneLigandsReceptors, Odorant

Identifiers

PMID40523847
PMCPMC12207589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.