Evidence map›Paper›PMID 40523466›Full record

ArticleContemporary clinical trials2025

Motivational Interviewing for Vaccine Uptake in Latinx Adults (MI Vacuna): Study protocol for a pragmatic multiple-period cluster-randomized crossover trial.

Rachel M Scrivano, Brittney J van de Water, Nicolle Rueras, Janin Alfonso, Kimberly H McManama O'Brien, Ximena Soto, Vannah Jiv S Caumeran, Barbara Mendez Campos, Michael Mancusi, Brian Diehl and 8 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06062056 (Leveraging Community-based Behavioral Health to Increase Vaccine Uptake in Latinx Adults With Mental Illness), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06062056 naterminatednot on this map

Leveraging Community-based Behavioral Health to Increase Vaccine Uptake in Latinx Adults With Mental Illness

TypeinterventionalSponsorBoston CollegeRan2023 to 2025Enrolled3,698ConditionsVaccine HesitancyArmsEHR alert, Motivational Interviewing, Warm hand off to nurse
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Rachel M ScrivanoSchool of Social Work, Boston College, Chestnut Hill, MA, USA. Electronic address: scrivanr@bc.edu.
Brittney J van de WaterConnell School of Nursing, Boston College, Chestnut Hill, MA, USA. Electronic address: sulligst@bc.edu.
Nicolle RuerasSchool of Social Work, Boston College, Chestnut Hill, MA, USA. Electronic address: rueras@bc.edu.
Janin AlfonsoNeighborHealth, Boston, MA, USA. Electronic address: alfonsoj@neighborhealth.com.
Kimberly H McManama O'BrienUnlimited Resilience LLC, Walpole, MA, USA; Behavioral Research and Training Institute, Piscataway, NJ, USA. Electronic address: khmobrien@gmail.com.
Ximena SotoSchool of Social Work, Boston College, Chestnut Hill, MA, USA. Electronic address: sotox@bc.edu.
Vannah Jiv S CaumeranSchool of Social Work, Boston College, Chestnut Hill, MA, USA. Electronic address: caumeran@bc.edu.
Barbara Mendez CamposSchool of Social Work, Boston College, Chestnut Hill, MA, USA. Electronic address: mendezba@bc.edu.
Michael MancusiNeighborHealth, Boston, MA, USA. Electronic address: mancusim@neighborhealth.com.
Brian DiehlNeighborHealth, Boston, MA, USA. Electronic address: diehlb@neighborhealth.com.
Elizabeth SouthwickNeighborHealth, Boston, MA, USA. Electronic address: eaton.liz@gmail.com.
Elisabeth MorenoNeighborHealth, Boston, MA, USA. Electronic address: morenoe@neighborhealth.com.
Celia BoraNeighborHealth, Boston, MA, USA. Electronic address: borac@neighborhealth.com.
Stephanie ArmbrusterHarvard T.H. Chan School of Public Health, Harvard University, Cambridge, MA, USA. Electronic address: sarmbruster@g.harvard.edu.
Nadia N AbuelezamConnell School of Nursing, Boston College, Chestnut Hill, MA, USA; Michigan State University, East Lansing, MI, USA. Electronic address: abueleza@msu.edu.
Rocío CalvoSchool of Social Work, Boston College, Chestnut Hill, MA, USA. Electronic address: rocio.calvo@bc.edu.
Sebastien HaneuseHarvard T.H. Chan School of Public Health, Harvard University, Cambridge, MA, USA. Electronic address: shaneuse@hsph.harvard.edu.
Kirsten K DavisonSchool of Social Work, Boston College, Chestnut Hill, MA, USA. Electronic address: kirsten.davison@bc.edu.

Funding

Leveraging community-based behavioral health to increase vaccine uptake in Latinx adults with mental illnessR01NR020482 · NINR · BOSTON COLLEGE · PI CALVO, ROCIO, DAVISON, KIRSTEN · 2022 to 2024
$1.7M
NINR NIH HHS R01 NR020482
6 · The paper itself

Abstract

backgroundWhile vaccines are safe and effective, vaccine hesitancy negatively impacts Latinx adults and adults with mental illness, resulting in low vaccination rates. Evidence suggests that Motivational interviewing (MI) may reduce vaccine hesitancy among underserved populations. This trial evaluates the effectiveness of MI integrated into behavioral health on vaccine hesitancy and COVID-19 and influenza vaccination among Latinx adults with mental illness.

methodsImplemented in partnership with NeighborHealth, a Federally Qualified Health Center (FQHC) in a predominantly-Latinx community, Motivational Interviewing for Vaccine Uptake in Latinx Adults (MI Vacuna) is a novel intervention, comprised of Motivational Interviewing (MI) and a warm handoff, implemented by behavioral health (BH) clinicians to address vaccine hesitancy in their patients. Utilizing a pragmatic multiple-period, cluster-randomized crossover trial design this study: 1) tests the effectiveness of MI Vacuna on COVID-19 and influenza vaccine uptake among Latinx adults with mental illness; 2) investigates moderators of intervention effects including patient-provider ethno-language concordance and country of origin; and 3) examines theory-based elements on the causal pathway between the intervention and vaccine uptake. Primary outcomes include patient COVID-19 and influenza vaccine uptake extracted from electronic health records. Secondary outcomes include vaccine hesitancy and provider trust, evaluated using patient surveys and interviews. Implementation outcomes are measured using multiple data sources. DISCUSSION: This novel study tests the effect of MI within the context of BH on COVID-19 and influenza vaccine hesitancy and uptake among Latinx adults. Results inform the sustainability and scale-up of MI Vacuna and BH-centered efforts to target patient vaccine hesitancy.

trial registrationclinicaltrials.gov, NCT06062056.

Indexed as

COVID-19 VaccinesHispanic or LatinoInfluenza VaccinesMental DisordersMotivational InterviewingVaccination HesitancyAdultCOVID-19Cross-Over StudiesFemaleHumansInfluenza, HumanMalePragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicVaccinationCOVID-19 VaccinesInfluenza VaccinesCOVID-19 vaccineHispanicInfluenza vaccineMental healthMotivational interviewingPragmatic trialVaccine hesitancy

Identifiers

PMID40523466
PMCPMC12925610

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.