Evidence map›Paper›PMID 40523235›Full record

ArticleMedicine and science in sports and exercise2025

Relationship between Changes in Physical Activity and Knee Health 18 Months after ACL Reconstruction.

David M Werner, Yvonne M Golightly, Michael D Rosenthal, Balasrinivasa Sajja, Chris Wichman, Melissa Manzer, Matt Tao, Elizabeth Wellsandt

Abstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yvonne M Golightly
Michael D RosenthalPhysical Therapy Program, College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE.
Balasrinivasa SajjaDepartment of Radiology, College of Medicine, University of Nebraska Medical Center, Omaha, NE.
Chris WichmanDepartment of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE.
Melissa ManzerPrivate Practice, Omaha, NE.
Matt Tao
Elizabeth Wellsandt

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI HOLSTEIN, SARAH A · 2016 to 2025
$42.8M
Osteoarthritis After ACL Injury: Establishing Cumulative Joint Loading as a Preventative TargetR21AR075254 · NIAMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WELLSANDT, ELIZABETH A · 2020 to 2021
$373k
NIAMS NIH HHS R21 AR075254NIGMS NIH HHS U54 GM115458
6 · The paper itself

Abstract

purposeThis study aimed to determine the relationship between changes in daily physical activity (PA) and knee health 18 months after anterior cruciate ligament reconstruction (ACLR). Knee health was defined using structural (quantitative magnetic resonance imaging) and functional (patient-reported and objectively measured knee function) constructs.

methodsEighteen individuals (83.3% female, 19.7 ± 5.6 yr old, BMI 23.9 ± 3.7 kg·m -2 ) completed testing. Daily steps over 1 wk and structural cartilage health, measured using a waist-worn accelerometer (Actigraph wGT3X-BT; ActiGraph Corp., Pensacola, FL) and T2 relaxation time on magnetic resonance imaging, respectively, were collected 6 and 18 months after ACLR. Eighteen months after ACLR, patient-reported and objectively measured knee health was assessed using the International Knee Documentation Committee Subjective Knee Form (IKDC) and isometric quadriceps strength, respectively. A linear regression model was used to test the relationship between the change in PA from 6 to 18 months after ACLR and the percentage change in T2 relaxation time of four cartilage regions (lateral and medial femoral and tibial cartilage) from 6 to 18 months after ACLR. A Fisher's exact test was used to assess the relationship between change in PA (increase/decrease) between 6 and 18 months after ACLR and adequate/inadequate knee function using patient-reported (IKDC) and objectively measured (quadriceps strength) knee function 18 months after ACLR.

resultsParticipants averaged 7547.3 ± 2439.7 daily steps 6 months after ACLR and 7504.9 ± 3736.3 daily steps 18 months after ACLR. There was no association between change in PA and structural knee health ( P = 0.069) or knee function ( P = 0.638).

conclusionsAverage daily steps did not change from 6 to 18 months after ACLR. PA from 6 to 18 months after ACLR was not associated with knee health outcomes at 18 months.

Indexed as

Anterior Cruciate Ligament ReconstructionExerciseKnee JointAccelerometryAdolescentAdultAnterior Cruciate Ligament InjuriesCartilage, ArticularFemaleHumansKneeMagnetic Resonance ImagingMaleMuscle StrengthPatient Reported Outcome MeasuresQuadriceps MuscleCARTILAGEDISABILITYKNEE FUNCTIONWALKING

Identifiers

PMID40523235
PMCPMC12767282

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.