Evidence map›Paper›PMID 40523138›Full record

Trial reportThe journal of extra-corporeal technology2025

Clinical evaluation of SafeCEC

Henrique Madureira da Rocha Coutinho, Joaquim Henrique de Souza Aguiar Coutinho, José Hamilton Torres, Rafaela Mourão Casanova, Gustavo Kikuta, Edison Emídio Reis

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The journal of extra-corporeal technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Henrique Madureira da Rocha CoutinhoDivision of Cardiovascular Surgery of the Hospital Universitário Pedro Ernesto - UERJ, Rua Boulevard 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil - Division of Cardiovascular Surgery of the Hospital das Clínicas de Teresópolis Costantino Ottaviano - UNIFESO, Avenida Alberto Torres, 111 - Alto, Teresópolis, RJ, 25964-004, Brazil.ORCID 0000-0003-2412-529X
Joaquim Henrique de Souza Aguiar CoutinhoDivision of Cardiovascular Surgery of the Hospital Universitário Pedro Ernesto - UERJ, Rua Boulevard 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil - Division of Cardiovascular Surgery of the Hospital das Clínicas de Teresópolis Costantino Ottaviano - UNIFESO, Avenida Alberto Torres, 111 - Alto, Teresópolis, RJ, 25964-004, Brazil.
José Hamilton TorresDivision of Cardiovascular Surgery of the Hospital Universitário Pedro Ernesto - UERJ, Rua Boulevard 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil.
Rafaela Mourão CasanovaDivision of Cardiovascular Surgery of the Hospital Universitário Pedro Ernesto - UERJ, Rua Boulevard 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil.
Gustavo KikutaDivision of Cardiovascular Surgery of the Hospital Universitário Pedro Ernesto - UERJ, Rua Boulevard 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil - Division of Cardiovascular Surgery of the Hospital das Clínicas de Teresópolis Costantino Ottaviano - UNIFESO, Avenida Alberto Torres, 111 - Alto, Teresópolis, RJ, 25964-004, Brazil.
Edison Emídio ReisDivision of Cardiovascular Surgery of the Hospital Universitário Pedro Ernesto - UERJ, Rua Boulevard 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn cardiopulmonary bypass (CPB), blood circulation is temporarily maintained by an artificial blood-pumping device during cardiac surgery. Worldwide, approximately half of the CPB procedures utilize either centrifugal or roller pumps (Wu P et al. Front Physiol 12, 699891). Centrifugal pumps, while non-occlusive, pose a risk of blood reflux if there is a system failure, which endangers patient safety (Souza MHL, Elias DO. Fundamentos da Circulação Extracorpórea 2006; 186-192). SafeCEC MATERIALS AND

methodsAfter approval by the Ethics Committee, 31 patients undergoing CPB with a centrifugal pump were included in the study. The patients were randomly divided into two groups: group A, where SafeCEC

resultsThis device has been shown to be effective in controlling blood reflux, eliminating the need for arterial line clamps. Analysis of plasma free hemoglobin levels revealed no significant differences between the groups with or without SafeCEC

conclusionThe SafeCEC

Indexed as

Cardiopulmonary BypassHemolysisAgedEquipment DesignFemaleHumansMaleMiddle AgedPilot ProjectsCardiopulmonary bypassCentrifugal pumpOne-way valveRetrograde flow

Identifiers

PMID40523138
PMCPMC12169719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.